Because of their potent antitumor activity and their proinflammatory role, natural killer (NK)
cells are at the forefront of efforts to develop immuno-oncologic treatments. NK cells …

Natural killer (NK) cells are the predominant innate lymphocyte subsets that mediate anti-
tumor and anti-viral responses, and therefore possess promising clinical utilization. NK cells …

Natural killer (NK) cells play indispensable roles in innate immune responses against tumor
progression. To depict their phenotypic and functional diversities in the tumor …

NK cells, lymphocytes of the innate immune system, are important for defense against
infectious pathogens and cancer. Classically, the CD56dim NK cell subset is thought to …

Natural killer (NK) cells are innate lymphoid cells that are important effectors in the first line
of defense toward transformed cells. This is mediated both by direct cytotoxic mechanisms …

NK cells are the major lymphocyte subset of the innate immune system that mediates
antiviral and anti-tumor responses. It is well established that they develop mechanisms to …

NK cells are key mediators of immune cell-mediated cytotoxicity toward infected and
transformed cells, being one of the main executors of cell death in the immune system. NK …

Alteration of the surface glycosylation pattern on malignant cells potentially affects tumor
immunity by directly influencing interactions with glycan-binding proteins (lectins) on the …

Natural killer (NK)–cell recognition of infected or neoplastic cells can induce cytotoxicity and
cytokine secretion. So far, it has been difficult to assess the relative contribution of multiple …

Human natural killer (NK) cells can be subdivided into different populations based on the
relative expression of the surface markers CD16 and CD56. The two major subsets are …