Subclinical thyroid disease (SCTD) is defined as serum free T4 and free T3 levels within
their respective reference ranges in the presence of abnormal serum TSH levels. SCTD is …

Foreword This Journal feature begins with a case vignette highlighting a common clinical
problem. Evidence supporting various strategies is then presented, followed by a review of …

Subclinical hypothyroidism is defined as an elevated serum TSH level associated with
normal total or free T4 and T3 values. The overall prevalence has been reported to range …

Objective: To evaluate whether subclinical hypothyroidism (SH) affects resting energy
expenditure (REE) as well as body composition, lipid profile, and serum leptin in obese …

The development of sensitive assays for thyrotropin (TSH) has led to the discovery that many
older patients have abnormal TSH levels without other alterations in serum thyroid hormone …

The end of the nineteenth century was a pivotal era in the history of thyroidology. Gull's
description of the syndrome of myxedema and Halsted's observation of" compensatory …

Hypothyroidism is associated with intrinsic myocardial changes reflected by alterations in
contractility and relaxation. Diastolic function, however, rather than systolic cardiac function …

Methods I have conducted a monthly Medline search for all articles on hypothyroidism for
five years. For this review I scanned these papers and background papers for a recent …

Objective: Many hypothyroid subjects receiving L-thyroxine (L-T4) complain of psychological
symptoms or cognitive dysfunction. However, there is limited validated information on these …

Every clinician knows the symptoms, signs, and laboratory abnormalities associated with
overt hyperthyroidism and hypothyroidism. Both conditions are unequivocally associated …