[HTML][HTML] Selenium: an antioxidant with a critical role in anti-aging

G Bjørklund, M Shanaida, R Lysiuk, H Antonyak… - Molecules, 2022 - mdpi.com
Aging is characterized by an imbalance between damage inflicted by reactive oxygen
species (ROS) and the antioxidative defenses of the organism. As a significant nutritional …

[HTML][HTML] Nanoparticles in clinical translation for cancer therapy

D Mundekkad, WC Cho - International journal of molecular sciences, 2022 - mdpi.com
The advent of cancer therapeutics brought a paradigm shift from conventional therapy to
precision medicine. The new therapeutic modalities accomplished through the properties of …

[HTML][HTML] Therapeutic potential and main methods of obtaining selenium nanoparticles

EG Varlamova, EA Turovsky, EV Blinova - International Journal of …, 2021 - mdpi.com
This review presents the latest data on the importance of selenium nanoparticles in human
health, their use in medicine, and the main known methods of their production by various …

[HTML][HTML] Immunomodulatory and anti-inflammatory properties of selenium-containing agents: Their role in the regulation of defense mechanisms against COVID-19

VN Mal'tseva, MV Goltyaev, EA Turovsky… - International Journal of …, 2022 - mdpi.com
The review presents the latest data on the role of selenium-containing agents in the
regulation of diseases of the immune system. We mainly considered the contributions of …

[HTML][HTML] Mesenchymal stromal cell-derived extracellular vesicles afford neuroprotection by modulating PI3K/AKT pathway and calcium oscillations

EA Turovsky, VV Golovicheva… - … Journal of Biological …, 2022 - ncbi.nlm.nih.gov
Mesenchymal stromal cells (MSC) are widely recognized as potential effectors in
neuroprotective therapy. The protective properties of MSC were considered to be associated …

[HTML][HTML] Role of selenium in viral infections with a major focus on SARS-CoV-2

SS Martinez, Y Huang, L Acuna, E Laverde… - International Journal of …, 2021 - mdpi.com
Viral infections have afflicted human health and despite great advancements in scientific
knowledge and technologies, continue to affect our society today. The current coronavirus …

[HTML][HTML] Features of the cytoprotective effect of selenium nanoparticles on primary cortical neurons and astrocytes during oxygen–glucose deprivation and …

EA Turovsky, VN Mal'Tseva, RM Sarimov… - Scientific Reports, 2022 - nature.com
The study is aimed at elucidating the effect of selenium nanoparticles (SeNPs) on the death
of cells in the primary culture of mouse cerebral cortex during oxygen and glucose …

[HTML][HTML] Modulatory effects of biosynthesized gold nanoparticles conjugated with curcumin and paclitaxel on tumorigenesis and metastatic pathways—in vitro and in …

SK Vemuri, S Halder, RR Banala… - International Journal of …, 2022 - mdpi.com
Background: Breast cancer is the most common cancer in women globally, and diagnosing it
early and finding potential drug candidates against multi-drug resistant metastatic breast …

[HTML][HTML] Size-dependent cytoprotective effects of selenium nanoparticles during oxygen-glucose deprivation in brain cortical cells

EG Varlamova, SV Gudkov, EY Plotnikov… - International Journal of …, 2022 - mdpi.com
It is known that selenium nanoparticles (SeNPs) obtained on their basis have a pleiotropic
effect, inducing the process of apoptosis in tumor cells, on the one hand, and protecting …

[HTML][HTML] Cytoprotective properties of a new nanocomplex of selenium with taxifolin in the cells of the cerebral cortex exposed to ischemia/reoxygenation

EG Varlamova, VV Khabatova, SV Gudkov… - Pharmaceutics, 2022 - mdpi.com
The neuroprotective effect of the natural antioxidant taxifolin (TAX) is well known for
ischemic pathologies. However, the limitations of taxifolin application are described—poor …