Role of the NF-κB signaling pathway in the pathogenesis of colorectal cancer
The NF-κB signaling pathway is a key regulator of CRC cell proliferation, apoptosis,
angiogenesis, inflammation, metastasis, and drug resistance. Over-activation of the NF-κB …
angiogenesis, inflammation, metastasis, and drug resistance. Over-activation of the NF-κB …
Advantages and drawbacks of dexamethasone in glioblastoma multiforme
The most widespread, malignant, and deadliest type of glial tumor is glioblastoma
multiforme (GBM). Despite radiation, chemotherapy, and radical surgery, the median …
multiforme (GBM). Despite radiation, chemotherapy, and radical surgery, the median …
G1/S cell cycle regulators mediate effects of circadian dysregulation on tumor growth and provide targets for timed anticancer treatment
Circadian disruption has multiple pathological consequences, but the underlying
mechanisms are largely unknown. To address such mechanisms, we subjected transformed …
mechanisms are largely unknown. To address such mechanisms, we subjected transformed …
Dexamethasone loaded liposomes by thin-film hydration and microfluidic procedures: formulation challenges
Liposomes have been one of the most exploited drug delivery systems in recent decades.
However, their large-scale production with low batch-to-batch differences is a challenge for …
However, their large-scale production with low batch-to-batch differences is a challenge for …
Harnessing hyaluronic acid-based nanoparticles for combination therapy: A novel approach for suppressing systemic inflammation and to promote antitumor …
Anti-inflammatory drugs such as dexamethasone (DEX) are commonly administered to
cancer patients along with anticancer drugs, however, the effect of DEX on human cancers …
cancer patients along with anticancer drugs, however, the effect of DEX on human cancers …
Dexamethasone inhibits pancreatic tumor growth in preclinical models: Involvement of activating glucocorticoid receptor
Y Yao, Q Yao, J Xue, X Tian, Q An, L Cui, C Xu… - Toxicology and Applied …, 2020 - Elsevier
Glucocorticoid receptor (GR) modulates extensive biological and pathological processes
including tumor progression through diverse mechanisms. The regulatory effects of …
including tumor progression through diverse mechanisms. The regulatory effects of …
Reactive oxygen species as mediators of disease progression and therapeutic response in colorectal cancer
Significance: Reactive oxygen species (ROS) are critical to normal cellular function with
redox homeostasis achieved by balancing ROS production with removal through …
redox homeostasis achieved by balancing ROS production with removal through …
Use of zebrafish larvae lateral line to study protection against cisplatin-induced ototoxicity: A scoping review
E Domarecka, M Skarzynska… - International journal …, 2020 - journals.sagepub.com
Aim: The present review aimed to consolidate and analyze the recent information about the
use of zebrafish in studies concerning cisplatin-induced ototoxicity and otoprotection …
use of zebrafish in studies concerning cisplatin-induced ototoxicity and otoprotection …
Caged Dexamethasone/Quercetin Nanoparticles, Formed of the Morphogenetic Active Inorganic Polyphosphate, are Strong Inducers of MUC5AC
M Neufurth, X Wang, S Wang, HC Schröder… - Marine Drugs, 2021 - mdpi.com
Inorganic polyphosphate (polyP) is a widely distributed polymer found from bacteria to
animals, including marine species. This polymer exhibits morphogenetic as well as antiviral …
animals, including marine species. This polymer exhibits morphogenetic as well as antiviral …
Novel primary human cancer stem-like cell populations from non-small cell lung cancer: inhibition of cell survival by targeting NF-κB and MYC signaling
BA Windmoeller, M Beshay, LP Helweg, C Flottmann… - Cells, 2021 - mdpi.com
There is growing evidence that cancer stem cells (CSCs), a small subpopulation of self-
renewal cancer cells, are responsible for tumor growth, treatment resistance, and cancer …
renewal cancer cells, are responsible for tumor growth, treatment resistance, and cancer …