Male infertility

A Agarwal, S Baskaran, N Parekh, CL Cho, R Henkel… - The Lancet, 2021 - thelancet.com
It is estimated that infertility affects 8–12% of couples globally, with a male factor being a
primary or contributing cause in approximately 50% of couples. Causes of male subfertility …

Oxidative stress and idiopathic male infertility

P Sengupta, S Roychoudhury, M Nath… - Oxidative Stress and …, 2022 - Springer
Idiopathic male infertility (IMI) refers to the condition where semen quality declines, but exact
causatives are not identified. This occurs in almost 30–40% of infertile men. Traditional …

Stem cell therapies for human infertility: advantages and challenges

JX Wu, T Xia, LP She, S Lin, XM Luo - Cell Transplantation, 2022 - journals.sagepub.com
Physical and mental health and hormonal imbalance are associated with the problems
related to infertility and reproductive disorders. The rate of infertility has increased globally …

Platelet lysate: a promising candidate in regenerative medicine

V Meftahpour, S Malekghasemi… - Regenerative …, 2021 - Future Medicine
Human platelet lysate has attracted much interest from many researchers as it is growth-
factor rich for cell expansion, which is employed as a new therapeutic strategy. Not only are …

[HTML][HTML] Cellular therapy via spermatogonial stem cells for treating impaired spermatogenesis, non-obstructive azoospermia

NE Abdelaal, BM Tanga, M Abdelgawad, S Allam… - Cells, 2021 - mdpi.com
Male infertility is a major health problem affecting about 8–12% of couples worldwide.
Spermatogenesis starts in the early fetus and completes after puberty, passing through …

Pathological roles of reactive oxygen species in male reproduction

S Chakraborty, S Roychoudhury - … Update on Male Infertility-Volume One, 2022 - Springer
Reactive oxygen species (ROS) are free radicals that have at least one unpaired electron
and play specific roles in the human body. An imbalance of ROS and antioxidant levels …

Efficacy of intrauterine administration of autologous peripheral blood mononuclear cells on the pregnancy outcomes in patients with recurrent implantation failure: A …

Z Pourmoghadam, S Abdolmohammadi-Vahid… - Journal of Reproductive …, 2020 - Elsevier
One in every nine couples suffers from implantation defects and pregnancy failures. In spite
of many contributions that ART has given to infertility treatment, there are many reports of the …

Stem cells technology as a platform for generating reproductive system organoids and treatment of infertility‐related diseases

Y Jahanbani, S Shafiee, S Davaran… - Cell Biology …, 2022 - Wiley Online Library
In recent years, stem cells have known as a helpful biological tool for the accurate diagnosis,
treatment and recognition of diseases. Using stem cells as biomarkers have presented high …

[HTML][HTML] Perspectives on potential fatty acid modulations of motility associated human sperm ion channels

A Cooray, JH Kim, MR Chae, S Lee… - International Journal of …, 2022 - mdpi.com
Human spermatozoan ion channels are specifically distributed in the spermatozoan
membrane, contribute to sperm motility, and are associated with male reproductive …

[HTML][HTML] Identification of hub genes associated with spermatogenesis by bioinformatics analysis

S Liu, Y Bian, W Wang, TJ Liu, T Zhang, Y Chang… - Scientific Reports, 2023 - nature.com
Spermatogenesis is a complex process related to male infertility. Till now, the critical genes
and specific mechanisms have not been elucidated clearly. Our objective was to determine …