The multifunctional membrane glycoprotein CD36 is expressed in different types of cells and
plays a key regulatory role in cellular lipid metabolism, especially in cardiac muscle. CD36 …

There is a constant high demand for energy to sustain the continuous contractile activity of
the heart, which is met primarily by the β-oxidation of long-chain fatty acids. The control of …

Heart disease is a leading cause of death worldwide. In many forms of heart disease,
including heart failure, ischaemic heart disease and diabetic cardiomyopathies, changes in …

Several epidemiological studies and clinical trials have reported the beneficial effects of
green tea, coffee, wine, and curry on human health, with its anti-obesity, anti-cancer, anti …

Long-chain fatty acids and lipids serve a wide variety of functions in mammalian
homeostasis, particularly in the formation and dynamic properties of biological membranes …

Skeletal muscle plays an important role in regulating whole-body energy expenditure given
it is a major site for glucose and lipid oxidation. Obesity and type 2 diabetes are causally …

White adipose tissue (WAT) plays an important role in the integration of whole-body
metabolism by storing fat and mobilizing triacylglycerol when needed. The released free …

Fatty acids are a major fuel source used to sustain contractile function in heart and oxidative
skeletal muscle. To meet the energy demands of these muscles, the uptake and β-oxidation …

Despite significant recent advances in precision medicine, pancreatic ductal
adenocarcinoma (PDAC) remains near uniformly lethal. Although immune-modulatory …

Increased accumulation of fatty acids and their derivatives can impair insulin-stimulated
glucose disposal by skeletal muscle. To characterize the nature of the defects in lipid …