A profile of the live biotherapeutic product RBX2660 and its role in preventing recurrent Clostridioides difficile infection
T Chopra - Expert Review of Anti-infective Therapy, 2023 - Taylor & Francis
Introduction Clostridiodes difficile infection (CDI) is a life-threatening illness that has been
labelled as an urgent threat by the Centers for Disease prevention (CDC). Areas Covered …
labelled as an urgent threat by the Centers for Disease prevention (CDC). Areas Covered …
The burden of CDI in the United States: a multifactorial challenge
P Feuerstadt, N Theriault, G Tillotson - BMC Infectious Diseases, 2023 - Springer
Clostridioides difficile infection (CDI) affects approximately 500,000 patients annually in the
United States, of these around 30,000 will die. CDI carries significant burdens including …
United States, of these around 30,000 will die. CDI carries significant burdens including …
Safety of fecal microbiota, live-jslm (REBYOTA™) in individuals with recurrent Clostridioides difficile infection: data from five prospective clinical trials
C Lee, T Louie, L Bancke… - Therapeutic …, 2023 - journals.sagepub.com
Background: Microbiota-based treatments reduce the incidence of recurrent Clostridioides
difficile infections (rCDIs), but prospectively collected safety data needed to broaden patient …
difficile infections (rCDIs), but prospectively collected safety data needed to broaden patient …
Effect of Fecal Microbiota, Live-Jslm (REBYOTA [RBL]) on Health-Related Quality of Life in Patients With Recurrent Clostridioides difficile Infection: Results From the …
KW Garey, ER Dubberke, A Guo… - Open Forum …, 2023 - academic.oup.com
Abstract Background Recurrence of Clostridioides difficile infection (rCDI) is common,
prolonging disease morbidity and leading to poor quality of life. We evaluated disease …
prolonging disease morbidity and leading to poor quality of life. We evaluated disease …
Cost-Effectiveness Analysis of REBYOTA™ (Fecal Microbiota, Live-jslm [FMBL]) Versus Standard of Care for the Prevention of Recurrent Clostridioides difficile …
T Lodise, A Guo, M Yang, EE Cook, W Song… - Advances in …, 2023 - Springer
Abstract Introduction Recurrent Clostridioides difficile infection (rCDI) is common and
associated with considerable clinical and economic consequences. REBYOTA™(fecal …
associated with considerable clinical and economic consequences. REBYOTA™(fecal …
Economic Impact of Recurrent Clostridioides difficile Infection in the USA: A Systematic Literature Review and Cost Synthesis
KR Reveles, M Yang, V Garcia-Horton, ML Edwards… - Advances in …, 2023 - Springer
Introduction Up to 35% of patients with a first episode of Clostridioides difficile infection (CDI)
develop recurrent CDI (rCDI), and of those, up to 65% experience multiple recurrences. A …
develop recurrent CDI (rCDI), and of those, up to 65% experience multiple recurrences. A …
Microbiome-Related and Infection Control Approaches to Primary and Secondary Prevention of Clostridioides difficile Infections
LV McFarland, EJC Goldstein, R Kullar - Microorganisms, 2023 - mdpi.com
Clostridioides difficile infections (CDIs) have decreased in the past years, but since 2021,
some hospitals have reported an increase in CDI rates. CDI remains a global concern and …
some hospitals have reported an increase in CDI rates. CDI remains a global concern and …
What's a Biofilm?—How the Choice of the Biofilm Model Impacts the Protein Inventory of Clostridioides difficile
M Brauer, C Lassek, C Hinze, J Hoyer… - Frontiers in …, 2021 - frontiersin.org
The anaerobic pathogen Clostridioides difficile is perfectly equipped to survive and persist
inside the mammalian intestine. When facing unfavorable conditions C. difficile is able to …
inside the mammalian intestine. When facing unfavorable conditions C. difficile is able to …
Budget Impact Analysis of REBYOTA™ (Fecal Microbiota, Live-jslm [FMBL]) for Preventing Recurrent Clostridioides difficile Infection in the US
T Lodise, A Guo, M Yang, EE Cook, W Song… - Advances in …, 2023 - Springer
Abstract Introduction Patients with Clostridioides difficile infection (CDI) often experience
recurrences (rCDI), which are associated with high morbidity, mortality, and healthcare …
recurrences (rCDI), which are associated with high morbidity, mortality, and healthcare …
The Role of Microbiome-Based Therapeutics in Clostridioides difficile Infection: Durable, Long-Term Results of RBX2660
R Orenstein - Infectious Diseases and Therapy, 2023 - Springer
A recently published manuscript described findings from a phase 2 open label study of the
microbiota-based live biotherapeutic product RBX2660 in patients with two or more previous …
microbiota-based live biotherapeutic product RBX2660 in patients with two or more previous …