Comorbidities associated with psoriatic arthritis: review and update

LM Perez-Chada, JF Merola - Clinical Immunology, 2020 - Elsevier
Psoriatic arthritis is an inflammatory arthropathy frequently associated with psoriasis and
several other comorbidities. The goal of this review is to summarize the available evidence …

Ustekinumab for extra-intestinal manifestations of inflammatory bowel disease: a systematic literature review

L Guillo, F D'amico, S Danese… - Journal of Crohn's and …, 2021 - academic.oup.com
Abstract Background and Aims Extra-intestinal manifestations [EIMs] are frequent in patients
with inflammatory bowel diseases [IBD] and are challenging conditions to manage. Tumour …

Recent advances of exosomes in immune-mediated eye diseases

N Li, L Zhao, Y Wei, VL Ea, H Nian, R Wei - Stem cell research & therapy, 2019 - Springer
Exosomes, nanosized extracellular vesicles of 30–150 nm, are shed by almost all cell types.
Bearing proteins, lipids, RNAs, and DNAs, exosomes have emerged as vital biological …

Biotherapies in uveitis

M Leclercq, AC Desbois, F Domont, G Maalouf… - Journal of clinical …, 2020 - mdpi.com
Non-infectious uveitis (NIU) represents one of the leading causes of blindness in developed
countries. The therapeutic strategy aims to rapidly control intra-ocular inflammation, prevent …

Cytokines that modulate the differentiation of Th17 cells in autoimmune uveitis

K Guo, X Zhang - Journal of immunology research, 2021 - Wiley Online Library
Increasing evidence has suggested that T helper 17 (Th17) cells play a central role in the
pathogenesis of ocular immune disease. The association between pathogenic Th17 cells …

Biologics for the treatment of noninfectious uveitis: current concepts and emerging therapeutics

AS Thomas - Current opinion in ophthalmology, 2019 - journals.lww.com
The TNF-α inhibitors adalimumab and infliximab have the greatest body of data supporting
their use in NIU. These agents are considered second-line therapy for most forms of NIU but …

Inflammatory cytokines as mediators of retinal endothelial barrier dysfunction in non‐infectious uveitis

LB Ferreira, KA Williams, G Best… - Clinical & …, 2023 - Wiley Online Library
Characterised by intraocular inflammation, non‐infectious uveitis includes a large group of
autoimmune and autoinflammatory diseases that either involve the eye alone or have both …

Psoriasis and uveitis: links and risks

C Fotiadou, E Lazaridou - Psoriasis: Targets and Therapy, 2019 - Taylor & Francis
Uveitis, an inflammatory disorder of the mid-portion of the eye, is considered a relatively rare
but very serious ocular complication of psoriasis. Data on the specific characteristics of …

Update on noninfectious uveitis in children and its treatment

I Maccora, ES Sen, AV Ramanan - Current Opinion in …, 2020 - journals.lww.com
Paediatric noninfectious uveitis is a sight-threatening condition and the identification of risk
factors and novel biomarkers is critical for tailored management. Biologic therapies are …

METTL3 inhibits autoreactive Th17 cell responses in experimental autoimmune uveitis via stabilizing ASH1L mRNA

L Zhao, Y Liu, B Ma, X Liu, R Wei, H Nian - The FASEB Journal, 2023 - Wiley Online Library
Abstract Methyltransferase like 3 (METTL3), a primary N6‐methyladenosine (m6A)
methyltransferase, has been implicated in various biological and pathological processes …