Synthetic biology: bottom-up assembly of molecular systems

S Hirschi, TR Ward, WP Meier, DJ Müller… - Chemical …, 2022 - ACS Publications
The bottom-up assembly of biological and chemical components opens exciting
opportunities to engineer artificial vesicular systems for applications with previously unmet …

Cracking open bacterial membrane vesicles

T Nagakubo, N Nomura, M Toyofuku - Frontiers in Microbiology, 2020 - frontiersin.org
Membrane vesicles (MVs) are nanoparticles composed of lipid membranes that are
produced by both Gram-negative and Gram-positive bacteria. MVs have been assigned …

Mechanism of membrane fusion: interplay of lipid and peptide

A Joardar, GP Pattnaik, H Chakraborty - The Journal of Membrane Biology, 2022 - Springer
Membrane fusion is an essential process for the survival of eukaryotes and the entry of
enveloped viruses into host cells. A proper understanding of the mechanism of membrane …

Fibroblasts as turned agents in cancer progression

R Wieder - Cancers, 2023 - mdpi.com
Simple Summary Normal epithelial cells in our organs are surrounded by stroma, which is
an ecosystem made up of a variety of cells and proteins that support their intended functions …

Interaction of nonsteroidal anti-inflammatory drugs with membranes: in vitro assessment and relevance for their biological actions

C Pereira-Leite, C Nunes, S Reis - Progress in lipid research, 2013 - Elsevier
Nonsteroidal anti-inflammatory drugs (NSAIDs) are among the most commonly used drugs
in the world due to their anti-inflammatory, analgesic and antipyretic properties …

How successful is nuclear targeting by nanocarriers?

SN Tammam, HME Azzazy, A Lamprecht - Journal of Controlled Release, 2016 - Elsevier
The nucleus is ultimately the final target for many therapeutics treating various disorders
including cancers, heart dysfunction and brain disorders. Owing to their specialized cell …

Direct cytosolic delivery of siRNA using nanoparticle‐stabilized Nanocapsules

Y Jiang, R Tang, B Duncan, Z Jiang, B Yan… - Angewandte …, 2015 - Wiley Online Library
The use of nanoparticle‐stabilized nanocapsules (NPSCs) for the direct cytosolic delivery of
siRNA is reported. In this approach, siRNA is complexed with cationic arginine …

Immunoliposome-mediated drug delivery to Plasmodium-infected and non-infected red blood cells as a dual therapeutic/prophylactic antimalarial strategy

E Moles, P Urbán, MB Jiménez-Díaz… - Journal of Controlled …, 2015 - Elsevier
One of the most important factors behind resistance evolution in malaria is the failure to
deliver sufficiently high amounts of drugs to early stages of Plasmodium-infected red blood …

Apoptosis‐induced cancer cell fusion: a mechanism of breast cancer metastasis

FK Noubissi, T Harkness, CM Alexander… - The FASEB …, 2015 - Wiley Online Library
Although cancer cell fusion has been suggested as a mechanism of cancer metastasis, the
underlying mechanisms defining this process are poorly understood. In a recent study …

[HTML][HTML] Computer modelling studies of the bilayer/water interface

M Pasenkiewicz-Gierula, K Baczynski… - … et Biophysica Acta (BBA …, 2016 - Elsevier
This review summarises high resolution studies on the interface of lamellar lipid bilayers
composed of the most typical lipid molecules which constitute the lipid matrix of …