Since their conception 50 years ago, molecularly imprinted polymers (MIPs) have seen
extensive development both in terms of synthetic routes and applications. Cells are perhaps …

Mobilization of hematopoietic stem and progenitor cells from the bone marrow into the
circulation by repetitive, daily stimulations with G-CSF alone, or in combination with …

Granulocyte colony-stimulating factor (G-CSF)–induced hematopoietic stem cell mobilization
is widely used for clinical transplantation; however, the mechanism is poorly understood. We …

Hematopoietic progenitor cells (HPCs) normally reside in the bone marrow (BM) but can be
mobilized into the peripheral blood (PB) after treatment with GCSF or chemotherapy. In …

Hematopoietic stem cell homing and engraftment require several adhesion interactions,
which are not fully understood. Engraftment of nonobese/severe combined …

The bone marrow vasuclar niche consists of a network of thin-walled and fenestrated
sinusoidal vessels whose integrity is maintained and supported by surrounding …

The receptor tyrosine kinase c-Kit and its ligand Stem Cell Factor (SCF) are essential for
haemopoiesis, melanogenesis and fertility. SCF acts at multiple levels of the haemopoietic …

Results to date indicate that high-dose therapy (HDT) with autologous stem cell support
improves survival of patients with symptomatic multiple myeloma (MM). We performed a …

Accumulating evidence indicates that interaction of stromal cell-derived factor 1 (SDF-
1/CXCL12 [CXC motif, ligand 12]) with its cognate receptor, CXCR4 (CXC motif, receptor 4) …

In concert with the International Society of Hematotherapy and Graft Engineering (ISHAGE),
we previously described a set of guidelines for detection of CD34+ cells based on a four …