[HTML][HTML] Long non-coding RNAs regulated NF-κB signaling in cancer metastasis: Micromanaging by not so small non-coding RNAs

S Ahmad, M Abbas, MF Ullah, MH Aziz… - Seminars in cancer …, 2022 - Elsevier
Cancer metastasis is a major reason for the cancer-associated deaths and a role of long non-
coding RNAs (lncRNAs) in cancer metastasis is increasingly being realized. Among the …

Phytocompound mediated blockage of quorum sensing cascade in ESKAPE pathogens

S Ghosh, D Lahiri, M Nag, A Dey, S Pandit, T Sarkar… - Antibiotics, 2022 - mdpi.com
Increased resistance of Enterococcus faecium, Staphylococcus aureus, Klebsiella
pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter …

Tannin extract from maritime pine bark exhibits anticancer properties by targeting the epigenetic UHRF1/DNMT1 tandem leading to the re-expression of TP73

W Ashraf, T Ahmad, NAR Almalki, M Krifa, L Zaayter… - Food & function, 2022 - pubs.rsc.org
Maritime pine bark is a rich source of polyphenolic compounds and is commonly employed
as a herbal supplement worldwide. This study was designed to check the potential of …

Pinostrobin attenuates azoxymethane-induced colorectal cytotoxicity in rats through augmentation of apoptotic Bax/Bcl-2 proteins and antioxidants

B Ali Abed Wahab, N Ain Salehen… - SAGE Open …, 2023 - journals.sagepub.com
Objectives: Pinostrobin (5-hydroxy-7-methoxyflavanone; PN) is a natural active ingredient
with numerous biological activities extensively utilized in tumour chemotherapy. The present …

Differential apoptotic effects of bee product mixtures on normal and cancer hepatic cells

V Sánchez-Martín, P Morales, A Iriondo-DeHond… - Antioxidants, 2023 - mdpi.com
Most effective anticancer drugs normally generate considerable cytotoxicity in normal cells;
therefore, the preferential activation of apoptosis in cancer cells and the reduction of toxicity …

Pinostrobin and tectochrysin conquer multidrug-resistant cancer cells via inhibiting P-glycoprotein ATPase

IT Wu, CY Kuo, CH Su, YH Lan, CC Hung - Pharmaceuticals, 2023 - mdpi.com
Enhanced drug efflux through ATP-binding cassette transporters, particularly P-glycoprotein
(P-gp), is a key mechanism underlying multidrug resistance (MDR). In the present study, we …

Research progress on the pharmacological effects and molecular mechanisms of pinostrobin

Z Wang, J Zhao, Y Chen, G Liu… - Natural Product …, 2023 - journals.sagepub.com
Pinostrobin (5-hydroxy-7-methoxyflavanone) is an active flavonoid substance. It is widely
present in many traditional Chinese herbs, including Carya cathayensis leaves …

An Abies Extract Containing Nonvolatile Polyphenols Shows Virucidal Activity against SARS-CoV-2 That Is Enhanced in Increased pH Conditions

I Maaroufi, D Jamsransuren, K Hashida, S Matsuda… - Pathogens, 2023 - mdpi.com
Researching the beneficial health properties of wood byproducts can prevent wastage by
turning them into valuable resources. In this study, the virucidal activity of two extracts from …

Artesunate, a new antimalarial clinical drug, exhibits potent anti‐AML activity by targeting the ROS/Bim and TFRC/Fe2+ pathways

Y Liu, H Li, Z Luo, Y Yu, J Yang… - British Journal of …, 2023 - Wiley Online Library
Background and Purpose Artesunate, approved by the Food and Drug Administration in
2020 as a new treatment for severe malaria, also shows anti‐tumour activity against acute …

[HTML][HTML] Pinostrobin attenuates azoxymethane-induced colorectal cytotoxicity in rats through augmentation of apoptotic Bax/Bcl-2 proteins and antioxidants

BAA Wahab, NA Salehen, MA Abdulla… - SAGE Open …, 2023 - ncbi.nlm.nih.gov
Objectives: Pinostrobin (5-hydroxy-7-methoxyflavanone; PN) is a natural active ingredient
with numerous biological activities extensively utilized in tumour chemotherapy. The present …