Phagocytosis is a primitive defense mechanism in all multicellular animals. Phagocytes such
as macrophages and neutrophils play an important role in limiting the dissemination of …

In 1857 Claude Bernard'introduced curare into the airways of a dog and discovered that the
drug pro-duced muscular paralysis. He also concluded that the walls of the bronchi were far …

Pulmonary microvascular injury, one of the earliest events in adult respiratory distress
syndrome (ARDS), is caused by the release of injurious products from stimulated neutrophils …

Study objective: To establish the natural history of lung injury in adult respiratory distress
syndrome (ARDS) in terms of increased pulmonary vascular permeability. Secondly, to …

This article reviews the contribution made by nuclear imaging to the assessment, diagnosis
and monitoring of patients with respiratory disease. It focuses on several specific areas …

Measurements of pulmonary clearance of inhaled 99mTc-DTPA and transvascular 113mIn-
transferrin flux were made in 12 patients with established ARDS and 14 volunteer control …

Although the clearance of an inhaled nebulised radioaerosol has long been employed as a
measure of lung function, this test has not found favour in nuclear medicine units to the …

Increased lung vascular permeability leading to increased plasma protein extravasation and
accumulation (PPA) is a characteristic feature of acute lung injury. Using a previously …

Acute pancreatitis has an incidence of approximately 50 cases per million of the United
Kingdom population and a mortality of 10–18%(1). Intrathoracic complications have been …

Pulmonary edema is a serious complication of heart failure, but often patients with chronic
heart failure resist pulmonary edema despite elevated pulmonary venous pressures. This …