Inhibitory TCR coreceptor PD-1 is a sensitive indicator of low-level replication of SIV and HIV-1

NC Salisch, DE Kaufmann, AS Awad… - The journal of …, 2010 - journals.aai.org
Ongoing antigenic stimulation appears to be an important prerequisite for the persistent
expression of programmed death 1 (PD-1), an inhibitory TCR coreceptor of the CD28 family …

Evidence for recombination of live, attenuated immunodeficiency virus vaccine with challenge virus to a more virulent strain

BR Gundlach, MG Lewis, S Sopper, T Schnell… - Journal of …, 2000 - Am Soc Microbiol
Live, attenuated immunodeficiency virus vaccines, such as nef deletion mutants, are the
most effective vaccines tested in the simian immunodeficiency virus (SIV) macaque model …

Antigen‐specific B cell detection reagents: use and quality control

MA Moody, BF Haynes - Cytometry Part A, 2008 - Wiley Online Library
Tests for immunoglobulin reactivity with specific antigens are some of the oldest and most
used assays in immunology. With efforts to understand B cell development, B cell …

Molecular mechanisms of HIV-1 associated neurodegeneration

H Ozdener - Journal of biosciences, 2005 - Springer
Since identification of the human immunodeficiency virus-1 (HIV-1), numerous studies
suggest a link between neurological impairments, in particular dementia, with acquired …

[HTML][HTML] Primate models of AIDS

SV Joag - Microbes and infection, 2000 - Elsevier
The primate models of AIDS provide insights into pathogenesis, transmission, and immune
responses to infection and are useful in testing vaccines and drugs. The HIV-1/chimpanzee …

Vaccine-elicited mucosal and systemic antibody responses are associated with reduced simian immunodeficiency viremia in infant rhesus macaques

K Jensen, R Nabi, KKA Van Rompay… - Journal of …, 2016 - Am Soc Microbiol
Despite significant progress in reducing peripartum mother-to-child transmission (MTCT) of
human immunodeficiency virus (HIV) with antiretroviral therapy (ART), continued access to …

Determinants of Increased Replicative Capacity of Serially Passaged Simian Immunodeficiency Virus with nef Deleted in Rhesus Monkeys

L Alexander, PO Illyinskii, SM Lang, RE Means… - Journal of …, 2003 - Am Soc Microbiol
Most rhesus macaques infected with simian immunodeficiency virus SIVmac239 with nef
deleted (either Δ nef or Δ nef Δ vpr ΔUS [Δ3]) control viral replication and do not progress to …

Enhanced simian immunodeficiency virus-specific immune responses in macaques induced by priming with recombinant Semliki Forest virus and boosting with …

C Nilsson, B Mäkitalo, P Berglund, F Bex, P Liljeström… - Vaccine, 2001 - Elsevier
The immunogenicity of two vector-based vaccines, either given alone or in a prime-boost
regimen, was investigated. Cynomolgus macaques were immunised with modified vaccinia …

Multiprotein HIV type 1 clade B DNA and MVA vaccines: construction, expression, and immunogenicity in rodents of the MVA component

LS Wyatt, PL Earl, JY Liu, JM Smith… - AIDS research and …, 2004 - liebertpub.com
Recombinant modified vaccinia virus Ankara (MVA) expressing SIV or SHIV Gag-Pol and
Env, alone or in conjunction with a related DNA vaccine, effectively controls …

Role of immune responses against the envelope and the core antigens of simian immunodeficiency virus SIVmne in protection against homologous cloned and …

PS Polacino, V Stallard, JE Klaniecki… - Journal of …, 1999 - Am Soc Microbiol
We previously showed that envelope (gp160)-based vaccines, used in a live recombinant
virus priming and subunit protein boosting regimen, protected macaques against …