Clinical use of digitalis: a state of the art review

TF Whayne Jr - American journal of cardiovascular drugs, 2018 - Springer
The history of digitalis is rich and interesting, with the first use usually attributed to William
Withering and his study on the foxglove published in 1785. However, some knowledge of …

Digoxin remains useful in the management of chronic heart failure

GW Dec - Medical Clinics, 2003 - medical.theclinics.com
Digoxin remains an important therapeutic option for the outpatient management of patients
with chronic symptomatic heart failure caused by systolic dysfunction. Randomized control …

A controlled study on oral propafenone versus digoxin plus quinidine in converting recent onset atrial fibrillation to sinus rhythm

A Capucci, G Boriani, I Rubino, S Della Casa… - International journal of …, 1994 - Elsevier
Eighty-seven patients with recent onset atrial fibrillation (≤ 8 days) without clinical signs of
heart failure were randomly allocated to one of the following treatments:(i) oral propafenone …

Desirable routine analytical goals for quantities assayed in serum

C Ricos - Eur J Clin Chem Clin Biochem, 1995 - degruyter.com
The aim of the Working Group was to describe guidelines for deriving desirable analytical
goals in laboratory medicine. First, a literature review is given of the different approaches …

A case series of hospitalized patients with elevated digoxin levels

PE Marik, L Fromm - The American journal of medicine, 1998 - Elsevier
PURPOSE: Although there is renewed enthusiasm for the use of digoxin in patients with
heart failure, current dosing guidelines are based on a nomogram published in 1974. We …

Itraconazole increases serum digoxin concentration

J Partanen, KM Jalava… - Pharmacology & …, 1996 - Wiley Online Library
Itraconazole can interact with several drugs by inhibiting their metabolism. Many drugs
known to increase serum digoxin concentration are inhibitors of CYP enzymes (eg …

Value of digoxin in heart failure and sinus rhythm: new features of an old drug?

DJ van VELDHUISEN, PA de GRAEFF… - Journal of the American …, 1996 - jacc.org
Digoxin has been a controversial drug since its introduction> 200 years ago. Although its
efficacy in patients with heart failure and atrial fibrillation is clear, its value in patients with …

An optical sensor for the determination of digoxin in serum samples based on a molecularly imprinted polymer membrane

GP González, PF Hernando, JSD Alegría - Analytica chimica acta, 2009 - Elsevier
This paper reports the synthesis and testing of a molecularly imprinted polymer membrane
for digoxin analysis. Digoxin-specific bulk polymer was obtained by the UV initiated co …

影响地高辛血浓度的因素及临床意义

李金恒 - 中国医院药学杂志, 1995 - cqvip.com
影响地高辛血浓度的因素及临床意义李金恒(南京军区南京总医院南京210002)
地高辛是临床常用的抗心功能不全药. 由于其安全范围窄, 药动学, 药效学个体差异大等原因 …

Digoxin for chronic heart failure: a review of the randomized controlled trials with special attention to the PROVED and RADIANCE trials

J Tauke, S Goldstein, M Gheorghiade - Progress in cardiovascular …, 1994 - Elsevier
Digitalis preparations have been used therapeutically for thousands of years. 1 The first
detailed description of digitalis was made by Withering in 1785, who noted that the drug …