[HTML][HTML] Sorting out the value of cruciferous sprouts as sources of bioactive compounds for nutrition and health

Á Abellán, R Domínguez-Perles, DA Moreno… - Nutrients, 2019 - mdpi.com
Edible sprouts with germinating seeds of a few days of age are naturally rich in nutrients and
other bioactive compounds. Among them, the cruciferous (Brassicaceae) sprouts stand out …

Broccoli consumption affects the human gastrointestinal microbiota

JL Kaczmarek, X Liu, CS Charron, JA Novotny… - The Journal of nutritional …, 2019 - Elsevier
The human gastrointestinal microbiota is increasingly linked to health outcomes; however,
our understanding of how specific foods alter the microbiota is limited. Cruciferous …

[HTML][HTML] The effects of nuclear factor erythroid 2 (NFE2)-related factor 2 (Nrf2) activation in preclinical models of peripheral neuropathic pain

P Basu, DL Averitt, C Maier, A Basu - Antioxidants, 2022 - mdpi.com
Oxidative stress, resulting from an imbalance between the formation of damaging free
radicals and availability of protective antioxidants, can contribute to peripheral neuropathic …

[HTML][HTML] Lack of effect of oral sulforaphane administration on Nrf2 expression in COPD: a randomized, double-blind, placebo controlled trial

RA Wise, JT Holbrook, G Criner, S Sethi, S Rayapudi… - PloS one, 2016 - journals.plos.org
Background COPD patients have high pulmonary and systemic oxidative stress that
correlates with severity of disease. Sulforaphane has been shown to induce expression of …

[HTML][HTML] The glucosinolates: a sulphur glucoside family of mustard anti-tumour and antimicrobial phytochemicals of potential therapeutic application

J Melrose - Biomedicines, 2019 - mdpi.com
This study reviewed aspects of the biology of two members of the glucosinolate family,
namely sinigrin and glucoraphanin and their anti-tumour and antimicrobial properties …

The potential use of l-sulforaphane for the treatment of chronic inflammatory diseases: A review of the clinical evidence

N Mazarakis, K Snibson, PV Licciardi, TC Karagiannis - Clinical nutrition, 2020 - Elsevier
Summary According to the World Health Organisation, 70% of all deaths globally can be
attributed to chronic inflammatory diseases such as rheumatoid arthritis, inflammatory bowel …

Isothiocyanates from Brassica Vegetables—Effects of Processing, Cooking, Mastication, and Digestion

T Oliviero, R Verkerk, M Dekker - Molecular nutrition & food …, 2018 - Wiley Online Library
The formation of health‐beneficial isothiocyanates (ITCs) from glucosinolates depends on a
wide variety of plant‐intrinsic factors (eg, concentration of glucosinolates, activity of …

[HTML][HTML] The world of Oral cancer and its risk factors viewed from the aspect of MicroRNA expression patterns

O Aghiorghiesei, O Zanoaga, A Nutu, C Braicu… - Genes, 2022 - mdpi.com
Oral cancer is one of the leading causes of death worldwide, with a reported 5-year survival
rate of around 50% after treatment. Epigenetic modifications are considered to have a key …

[HTML][HTML] Current perspectives of mitochondria-targeted antioxidants in cancer prevention and treatment

RA Zinovkin, KG Lyamzaev… - Frontiers in Cell and …, 2023 - frontiersin.org
Oxidative stress nearly always accompanies all stages of cancer development. At the early
stages, antioxidants may help to reduce reactive oxygen species (ROS) production and …

[HTML][HTML] Anticancer properties of sulforaphane: current insights at the molecular level

M Asif Ali, N Khan, N Kaleem, W Ahmad… - Frontiers in …, 2023 - frontiersin.org
Sulforaphane (SFN) is an isothiocyanate with multiple biomedical applications.
Sulforaphane can be extracted from the plants of the genus Brassica. However, broccoli …