[HTML][HTML] Neuroinflammation as a common feature of neurodegenerative disorders
L Guzman-Martinez, RB Maccioni, V Andrade… - Frontiers in …, 2019 - frontiersin.org
Neurodegenerative diseases share the fact that they derive from altered proteins that
undergo an unfolding process followed by formation of β-structures and a pathological …
undergo an unfolding process followed by formation of β-structures and a pathological …
Clinical neurology and epidemiology of the major neurodegenerative diseases
MG Erkkinen, MO Kim… - Cold Spring Harbor …, 2018 - cshperspectives.cshlp.org
Neurodegenerative diseases are a common cause of morbidity and cognitive impairment in
older adults. Most clinicians who care for the elderly are not trained to diagnose these …
older adults. Most clinicians who care for the elderly are not trained to diagnose these …
Frontotemporal dementia
J Bang, S Spina, BL Miller - The Lancet, 2015 - thelancet.com
Frontotemporal dementia is an umbrella clinical term that encompasses a group of
neurodegenerative diseases characterised by progressive deficits in behaviour, executive …
neurodegenerative diseases characterised by progressive deficits in behaviour, executive …
[PDF][PDF] Converging mechanisms in ALS and FTD: disrupted RNA and protein homeostasis
Breakthrough discoveries identifying common genetic causes for amyotrophic lateral
sclerosis (ALS) and frontotemporal dementia (FTD) have transformed our view of these …
sclerosis (ALS) and frontotemporal dementia (FTD) have transformed our view of these …
The epidemiology of frontotemporal dementia
CU Onyike, J Diehl-Schmid - International review of psychiatry, 2013 - Taylor & Francis
Frontotemporal dementia, a heterogeneous neurodegenerative disorder, is a common
cause of young onset dementia (ie dementia developing in midlife or earlier). The estimated …
cause of young onset dementia (ie dementia developing in midlife or earlier). The estimated …
Clinical spectrum of amyotrophic lateral sclerosis (ALS)
Amyotrophic lateral sclerosis (ALS) is primarily characterized by progressive loss of motor
neurons, although there is marked phenotypic heterogeneity between cases. Typical, or …
neurons, although there is marked phenotypic heterogeneity between cases. Typical, or …
Whole-genome sequencing reveals important role for TBK1 and OPTN mutations in frontotemporal lobar degeneration without motor neuron disease
Frontotemporal lobar degeneration with TAR DNA-binding protein 43 inclusions (FTLD-
TDP) is the most common pathology associated with frontotemporal dementia (FTD). Repeat …
TDP) is the most common pathology associated with frontotemporal dementia (FTD). Repeat …
The role of FUS gene variants in neurodegenerative diseases
H Deng, K Gao, J Jankovic - Nature Reviews Neurology, 2014 - nature.com
The neurodegenerative diseases are a diverse group of disorders characterized by
progressive loss of specific groups of neurons. These diseases affect different populations …
progressive loss of specific groups of neurons. These diseases affect different populations …
Interplay of endoplasmic reticulum stress and autophagy in neurodegenerative disorders
The common underlying feature of most neurodegenerative diseases such as Alzheimer
disease (AD), prion diseases, Parkinson disease (PD), and amyotrophic lateral sclerosis …
disease (AD), prion diseases, Parkinson disease (PD), and amyotrophic lateral sclerosis …
hnRNP A3 binds to GGGGCC repeats and is a constituent of p62-positive/TDP43-negative inclusions in the hippocampus of patients with C9orf72 mutations
Genetic analysis revealed the hexanucleotide repeat expansion GGGGCC within the
regulatory region of the gene C9orf72 as the most common cause of familial amyotrophic …
regulatory region of the gene C9orf72 as the most common cause of familial amyotrophic …