Cell-type-specific expression of tRNAs in the brain regulates cellular homeostasis
Defects in tRNA biogenesis are associated with multiple neurological disorders, yet our
understanding of these diseases has been hampered by an inability to determine tRNA …
understanding of these diseases has been hampered by an inability to determine tRNA …
Design, synthesis and biological evaluation of novel tubulin-targeting agents with a dual-mechanism for polymerization inhibition and protein degradation
S Wang, J Wang, X Lu, M Liu, Y Liu, M Li… - European Journal of …, 2024 - Elsevier
Microtubules are recognized as one of the most vital and attractive targets in anticancer
therapy. The development of novel tubulin-targeting agents with a new action mechanism is …
therapy. The development of novel tubulin-targeting agents with a new action mechanism is …
Distribution and Functional Significance of KLF15 in Mouse Cerebellum
D Li, S Cao, Y Chen, Y Liu, K Huo, Z Shi, S Han… - 2024 - researchsquare.com
Abstract Kruppel-like factor 15 (KLF15), a member of the KLF family, is closely involved in
many biological processes. However, the mechanism by which KLF15 regulates neural …
many biological processes. However, the mechanism by which KLF15 regulates neural …