A large number of clinical trials have shown stem cell therapy to be a promising therapeutic
approach for the treatment of cardiovascular diseases. Since the first transplantation into …

Gallic acid, a predominant polyphenol, has been shown to inhibit carcinogenesis in animal
models and in vitro cancerous cell lines. The inhibitory effect of gallic acid on cancer cell …

The α‐chemokine stromal‐derived factor (SDF)‐1 and the G‐protein–coupled seven‐span
transmembrane receptor CXCR4 axis regulates the trafficking of various cell types. In this …

By employing multiparameter sorting, we identified in murine bone marrow (BM) a
homogenous population of rare (∼ 0.02% of BMMNC) Sca-1+ lin− CD45− cells that express …

Aims Comparison of intracoronary infusion of bone marrow (BM)-derived unselected
mononuclear cells (UNSEL) and selected CD34+ CXCR4+ cells (SEL) in patients with acute …

Proper response of normal stem cells (NSC) to motomorphogens and chemoattractants
plays a pivotal role in organ development and renewal/regeneration of damaged tissues …

Clinical trials of bone marrow stem/progenitor cell therapy after myocardial infarction (MI)
have shown promising results, but the mechanism of benefit is unclear. We examined the …

Bone-marrow-derived EPCs (endothelial progenitor cells) play an integral role in the
regulation and protection of the endothelium, as well as new vessel formation. Peripheral …

The chemokine SDF-1 (CXCL12) and its receptor CXCR4 are involved in regulation of
migration, survival, and development of multiple cell types, including human hematopoietic …

Myocardial infarction is associated with persistent muscle damage, scar formation and
depressed cardiac performance. Recent studies have demonstrated the clinical significance …