[HTML][HTML] Human endogenous retrovirus K (HML-2) in health and disease
B Xue, LA Sechi, DJ Kelvin - Frontiers in microbiology, 2020 - frontiersin.org
Human endogenous retroviruses (HERVs) are derived from exogenous retrovirus infections
in the evolution of primates and account for about 8% of the human genome. They were …
in the evolution of primates and account for about 8% of the human genome. They were …
[HTML][HTML] Anti-HERV-K drugs and vaccines, possible therapies against tumors
S Hosseiniporgham, LA Sechi - Vaccines, 2023 - mdpi.com
The footprint of human endogenous retroviruses (HERV), specifically HERV-K, has been
found in malignancies, such as melanoma, teratocarcinoma, osteosarcoma, breast cancer …
found in malignancies, such as melanoma, teratocarcinoma, osteosarcoma, breast cancer …
[HTML][HTML] Human endogenous retrovirus K in the respiratory tract is associated with COVID-19 physiopathology
JR Temerozo, N Fintelman-Rodrigues, MC Dos Santos… - Microbiome, 2022 - Springer
Background Critically ill 2019 coronavirus disease (COVID-19) patients under invasive
mechanical ventilation (IMV) are 10 to 40 times more likely to die than the general …
mechanical ventilation (IMV) are 10 to 40 times more likely to die than the general …
Expression of human endogenous retrovirus group K (HERV-K) HML-2 correlates with immune activation of macrophages and type I interferon response
E Russ, N Mikhalkevich, S Iordanskiy - Microbiology Spectrum, 2023 - Am Soc Microbiol
Human endogenous retroviruses (HERVs) comprise about 8.3% of the human genome and
are capable of producing RNA molecules that can be sensed by pattern recognition …
are capable of producing RNA molecules that can be sensed by pattern recognition …
[HTML][HTML] HERV-K and HERV-H Env proteins induce a humoral response in prostate cancer patients
A higher expression of human endogenous retroviruses (HERVs) has been associated with
several malignancies, including prostate cancer, implying a possible use as a diagnostic or …
several malignancies, including prostate cancer, implying a possible use as a diagnostic or …
[HTML][HTML] High expression of HERV-K (HML-2) might stimulate interferon in COVID-19 patients
Y Guo, C Yang, Y Liu, T Li, H Li, J Han, L Jia, X Wang… - Viruses, 2022 - mdpi.com
Background. Interferon is a marker of host antiviral immunity, which is disordered in COVID-
19 patients. ERV can affect the secretion of interferon through the cGAS-STING pathway. In …
19 patients. ERV can affect the secretion of interferon through the cGAS-STING pathway. In …
[HTML][HTML] Human Endogenous Retrovirus-K (HML-2)-Related Genetic Variation: Human Genome Diversity and Disease
Human endogenous retroviruses (HERVs) comprise a significant portion of the human
genome, making up roughly 8%, a notable comparison to the 2–3% represented by coding …
genome, making up roughly 8%, a notable comparison to the 2–3% represented by coding …
p53 Binding sites in long terminal repeat 5Hs (LTR5Hs) of human endogenous retrovirus K family (HML-2 subgroup) play important roles in the regulation of LTR5Hs …
M Liu, L Jia, H Li, Y Liu, J Han, X Wang, T Li… - Microbiology …, 2022 - Am Soc Microbiol
The long terminal repeats (LTRs) of human endogenous retroviruses (HERVs) are
distributed throughout the human genome and provide favorable conditions to regulate the …
distributed throughout the human genome and provide favorable conditions to regulate the …
HERV-K (HML-2) insertion polymorphisms in the 8q24. 13 region and their potential etiological associations with acute myeloid leukemia
N Camargo-Forero, S Orozco-Arias… - Archives of …, 2023 - Springer
Human endogenous retroviruses (HERVs) are LTR retrotransposons that are present in the
human genome. Among them, members of the HERV-K (HML-2) group are suspected to …
human genome. Among them, members of the HERV-K (HML-2) group are suspected to …
[HTML][HTML] HERVK-mediated regulation of neighboring genes: implications for breast cancer prognosis
B Liang, T Yan, H Wei, D Zhang, L Li, Z Liu, W Li… - Retrovirology, 2024 - Springer
Human endogenous retroviruses (HERVs) are the remnants of ancient retroviral infections
integrated into the human genome. Although most HERVs are silenced or rendered inactive …
integrated into the human genome. Although most HERVs are silenced or rendered inactive …