[HTML][HTML] Protein acetylation going viral: implications in antiviral immunity and viral infection

M Xue, T Feng, Z Chen, Y Yan, Z Chen… - International Journal of …, 2022 - mdpi.com
During viral infection, both host and viral proteins undergo post-translational modifications
(PTMs), including phosphorylation, ubiquitination, methylation, and acetylation, which play …

[HTML][HTML] Influenza A Virus and Acetylation: The Picture Is Becoming Clearer

M Husain - Viruses, 2024 - mdpi.com
Influenza A virus (IAV) is one of the most circulated human pathogens, and influenza
disease, commonly known as the flu, remains one of the most recurring and prevalent …

Protein arginine methyltransferase 5 mediates arginine symmetric dimethylation of influenza A virus PB2 and supports viral replication

H Sun, S Tu, D Luo, C Dai, M Jin… - Journal of medical …, 2023 - Wiley Online Library
Influenza A virus (IAV) relies on intricate and highly coordinated associations with host
factors for efficient replication and transmission. Characterization of such factors holds great …

[HTML][HTML] Human N-alpha-acetyltransferase 60 promotes influenza A virus infection by dampening the interferon alpha signaling

F Ahmed, M Husain - Frontiers in Immunology, 2022 - frontiersin.org
N-alpha-acetyltransferase 60 (NAA60) is the most recently discovered N-terminal
acetyltransferase and found only in multicellular eukaryotes. NAA60 localizes to the Golgi …

[HTML][HTML] Deacetylation of ACO2 Is Essential for Inhibiting Bombyx mori Nucleopolyhedrovirus Propagation

M Hu, Y You, Y Li, S Ma, J Li, M Miao, Y Quan, W Yu - Viruses, 2023 - mdpi.com
Bombyx mori nucleopolyhedrovirus (BmNPV) is a specific pathogen of Bombyx mori that can
significantly impede agricultural development. Accumulating evidence indicates that the viral …

[HTML][HTML] Targeting the YXXΦ Motifs of the SARS Coronaviruses 1 and 2 ORF3a Peptides by In Silico Analysis to Predict Novel Virus—Host Interactions

A Kakkanas, E Karamichali, EI Koufogeorgou… - Biomolecules, 2022 - mdpi.com
The emerging SARS-CoV and SARS-CoV-2 belong to the family of “common cold” RNA
coronaviruses, and they are responsible for the 2003 epidemic and the current pandemic …

Comparative kinase activity profiling of pathogenic influenza A viruses reveals new anti-and pro-viral protein kinases

L Liu, A Weiß, VV Saul… - Journal of General …, 2022 - microbiologyresearch.org
Constant evolution of influenza A viruses (IAVs) leads to the occurrence of new virus strains,
which can cause epidemics and occasional pandemics. Here we compared two medically …

Functionality of IAV packaging signals depends on site-specific charges within the viral nucleoprotein

K Ciminski, V Flore, C Jakob, H Mues… - Journal of …, 2024 - Am Soc Microbiol
The coordinated packaging of the segmented genome of the influenza A virus (IAV) into
virions is an essential step of the viral life cycle. This process is controlled by the interaction …

Pirh2 restricts influenza A virus replication by modulating short‐chain ubiquitination of its nucleoprotein

H Chen, X Gao, S Zhao, C Bao, X Ming… - The FASEB …, 2022 - Wiley Online Library
Influenza A viruses (IAVs) rely on viral ribonucleoprotein (vRNP) complexes to control
transcription and replication. Each vRNP consists of one viral genomic RNA segment …

Structural flexibility and heterogeneity of recombinant human glial fibrillary acidic protein (GFAP)

D Gogishvili, E Illes‐Toth, MJ Harris… - Proteins: Structure …, 2024 - Wiley Online Library
Glial fibrillary acidic protein (GFAP) is a promising biomarker for brain and spinal cord
disorders. Recent studies have highlighted the differences in the reliability of GFAP …