The human epidermal growth factor receptor 2 (HER2) is overexpressed in 13–22% of
breast cancers (BC). Approximately 60–70% of HER2+ BC co-express hormone receptors …

Simple Summary Breast cancer remains the most commonly diagnosed cancer and the
leading cause of cancer death among females worldwide. It is a highly heterogeneous …

Progesterone, the ovarian steroid hormone, regulates a plentitude of biological processes in
tissues ranging from the brain to bones. Recognizing the role of progesterone and its …

Background A biopsy of first recurrence or metastatic disease is recommended to re-
evaluate oestrogen receptor status in patients with breast cancer and to select appropriate …

Since the discovery of the anticancer potential of ruthenium-based complexes, several
species were reported as promising candidates for the treatment of breast cancer, which …

Breast cancer is the most frequently diagnosed cancer and the leading cause of death by
cancer among women worldwide. The prognosis of the disease and patients' response to …

Colorectal cancer is a sporadic, hereditary, or familial based disease in its origin, caused
due to diverse set of mutations in large intestinal epithelial cells. Colorectal cancer (CRC) is …

Estrogen is the major mitogenic stimulus of mammary gland development during puberty
wherein ER signaling acts to induce abundant PR expression. PR signaling, in contrast, is …

We have recently demonstrated that fibroblast growth factor receptor 2 (FGFR2)‐mediated
signalling alters progesterone receptor (PR) activity and response of oestrogen receptor α …

Curcumin, a potent phytochemical derived from the spice element turmeric, has been
identified as a herbal remedy decades ago and has displayed promise in the field of …