Background and objective microRNAs (miR or miRNAs) function as onco-enhancers and
tumor suppressors. In some cases, they play a dual role in organ-specific/tissue-specific …

Abstract Stromal-interaction molecule 1 (STIM1)-mediated store-operated Ca 2+ entry
(SOCE) plays a key role in mediating cardiomyocyte hypertrophy, both in vitro and in vivo …

We examined the effect of ginsenoside Re (G-Re) on autophagy in H9c2 cardiomyocytes
cultured in glucose deprivation (GD). Levels of the membrane-bound autophagy-related …

Autophagy is implicated in the maintenance of cardiac homeostasis. Autophagy is activated
in heart failure, in which reactive oxygen species (ROS) are increased. Exogenous ROS …

Cardiac stromal cells (CSCs) embrace multiple phenotypes and are a contributory factor in
tissue homeostasis and repair. They can be exploited as therapeutic mediators against …

Glycyrrhetinic acid (GA) is an ingredient of triterpene saponins found in Gancao (Radix
Glycyrrhizae). Here, we investigated the protective effects of GA in H9c2 cells, and explored …

Stress responses are important to human physiology and pathology, and the inability to
adapt to cellular stress leads to cell death. To mitigate cellular stress and re-establish …

As a common complication of glycemic control in patients with diabetes, hypoglycemia often
leads to brain dysfunction or damage. To identify new mechanisms underlying hypoglycemic …

Diabetes is diagnosed on the basis of hyperglycemia; in particular, non-fasting plasma
glucose of 200 mg/dl or fasting plasma glucose of 126 mg/dl. Pre-diabetic hyperglycemic …