The lymphatic system serves an integral role in fluid homeostasis, lipid metabolism and
immune control. In cancer, the lymph nodes that drain solid tumours are a primary site of …

The generation of new lymphatic vessels through lymphangiogenesis and the remodelling
of existing lymphatics are thought to be important steps in cancer metastasis. The past …

Malignant tumors release growth factors such as VEGF-C to induce lymphatic vessel
expansion (lymphangiogenesis) in primary tumors and in draining sentinel LNs, thereby …

The lymphatic system plays critical roles in tissue fluid homeostasis and immunity and has
been implicated in the development of many different pathologies, ranging from …

Obesity is a key risk factor for metabolic and cardiovascular diseases, and although we
understand the mechanisms regulating weight and energy balance, the causes of some …

Traditionally, tumor-associated lymphatic vessels have been regarded as passive by-
standers, serving simply as a drainage system for interstitial fluid generated within the tumor …

Visualization of the lymphatic system is clinically necessary during diagnosis or treatment of
many conditions and diseases; it is used for identifying and monitoring lymphedema, for …

Accounting for 16 million new cases and 9 million deaths annually, cancer leaves a great
number of patients helpless. It is a complex disease and still a major challenge for the …

The two vascular systems of our body are the blood and the lymphatic vasculature. Our
understanding of the genes and molecular mechanisms controlling the development of the …

Purpose We previously found that ophthalmic formulations containing nanoparticles
prepared by a bead mill method lead to an increase in bioavailability in comparison with …