Landscape of adrenal tumours in patients with congenital adrenal hyperplasia

M Carsote, AM Gheorghe, C Nistor, AI Trandafir… - Biomedicines, 2023 - mdpi.com
Our aim is to update the topic of adrenal tumours (ATs) in congenital adrenal hyperplasia
(CAH) based on a multidisciplinary, clinical perspective via an endocrine approach. This …

Sexually dimorphic activation of innate antitumor immunity prevents adrenocortical carcinoma development

JJ Wilmouth Jr, J Olabe, D Garcia-Garcia, C Lucas… - Science …, 2022 - science.org
Unlike most cancers, adrenocortical carcinomas (ACCs) are more frequent in women than in
men, but the underlying mechanisms of this sexual dimorphism remain elusive. Here, we …

Adrenocortical Carcinomas: Molecular Pathogenesis, Treatment Options, and Emerging Immunotherapy and Targeted Therapy Approaches

D Chukkalore, K MacDougall, V Master… - The …, 2024 - academic.oup.com
Adrenocortical carcinoma (ACC) is a rare and aggressive malignancy in the advanced
setting with poor prognosis. This narrative review provides an overview of the epidemiology …

[HTML][HTML] N7-methylguanosine regulatory genes well represented by METTL1 define vastly different prognostic, immune and therapy landscapes in adrenocortical …

F Xu, D Cai, S Liu, K He, J Chen, L Qu… - American Journal of …, 2023 - ncbi.nlm.nih.gov
Abstract Although N7-methylguanosine (m7G) is one of the most frequent RNA
modifications, it has received little attention. Adrenocortical carcinoma (ACC) is a highly …

Adrenal mass biopsy in patients without extraadrenal primary malignancy: a multicenter study

S Krishna, BM Moloney, B Bao… - American Journal of …, 2024 - Am Roentgen Ray Soc
BACKGROUND. Adrenal washout CT is not useful for evaluating incidental adrenal masses
in patients without known or suspected primary extraadrenal malignancy. OBJECTIVE. The …

Was it an adrenocortical adenoma or an adrenocortical carcinoma? Limitation of the weiss scoring system in determining the malignant potential of adrenocortical …

CL Wong, CK Fok, YK Chan, VHK Tam… - Case Reports in …, 2022 - Wiley Online Library
Background. Adrenocortical carcinoma (ACC) is a rare endocrine malignancy. An accurate
diagnosis of ACC is of paramount importance as it greatly impacts the management and …

[HTML][HTML] Potential ophthalmological side effects induced by anti-neoplastic regimens for the treatment of genitourinary cancers: a review

M Sakellakis, N Spathas, KT Tsaousis, EN Nikitiadis… - Cureus, 2022 - ncbi.nlm.nih.gov
The outcomes of patients with genitourinary (GU) cancers have been steadily improving in
recent years. Novel therapies have entered our armamentarium, while several other …

Estimation of the tumor size at cure threshold among adult patients with adrenocortical carcinoma: A populational-based study

Y Huang, L Liu, Q Gan, Z Shen, Y Yao, C Liao, S Lu… - Heliyon, 2024 - cell.com
Background The prognostic significance of tumor size with adrenocortical carcinoma (ACC)
patients has not yet been thoroughly evaluated. Our objective was to investigate the …

Prognosis and Therapeutic Efficacy Prediction of Adrenocortical Carcinoma Based on a Necroptosis‐Associated Gene Signature

D Ji, R Zhong, S Fan - BioMed Research International, 2022 - Wiley Online Library
Background. Adrenocortical carcinoma (ACC) is a rare and poor prognosis malignancy.
Necroptosis is a special type of cell apoptosis, which is regulated in caspase‐independent …

Machine learning combining multi-omics data and network algorithms identifies adrenocortical carcinoma prognostic biomarkers

R Martin-Hernandez, S Espeso-Gil… - Frontiers in Molecular …, 2023 - frontiersin.org
Background: Rare endocrine cancers such as Adrenocortical Carcinoma (ACC) present a
serious diagnostic and prognostication challenge. The knowledge about ACC pathogenesis …