Prognostic factors of biochemical remission after transsphenoidal surgery for acromegaly: a structured review

N Agrawal, AG Ioachimescu - Pituitary, 2020 - Springer
Purpose Biochemical control is the main determinant of survival, clinical manifestations and
comorbidities in acromegaly. Transsphenoidal selective adenomectomy (TSA) is the initial …

Management of growth hormone–secreting pituitary adenomas causing acromegaly: a practical review of surgical and multimodal management strategies for …

SK Cheok, JD Carmichael, G Zada - Journal of Neurosurgery, 2023 - thejns.org
This review aimed to highlight the history, diagnostic criteria, preoperative prognostic factors,
surgical management, and multimodal adjuvant therapies recommended to provide a …

Predictors of surgical outcome and early criteria of remission in acromegaly

X Antunes, N Ventura, GB Camilo, LE Wildemberg… - Endocrine, 2018 - Springer
Background Transsphenoidal surgery (TSS) is the cornerstone of acromegaly treatment,
however there are no robust predictors of surgical outcome and remission can only be …

Endoscopic transsphenoidal approach for acromegaly with remission rates in 401 patients: 2010 consensus criteria

I Anik, B Cabuk, A Gokbel, A Selek, B Cetinarslan… - World Neurosurgery, 2017 - Elsevier
Background Transsphenoidal surgery is the first-choice treatment for acromegaly.
Postoperative remission is an important predictor of outcome. Various factors have been …

The prognostic-based approach in growth hormone-secreting pituitary neuroendocrine tumors (PitNET): Tertiary reference center, single senior surgeon, and long …

A Ferrés, L Reyes, A Di Somma, T Topczewski… - Cancers, 2022 - mdpi.com
Simple Summary Pituitary neuroendocrine tumors (PitNET) are characterized to present a
heterogeneous behavior, and growth hormone (GH)-secreting PitNET is not an exception …

Machine learning as a clinical decision support tool for patients with acromegaly

C Sulu, AB Bektaş, S Şahin, E Durcan, Z Kara… - Pituitary, 2022 - Springer
Objective To develop machine learning (ML) models that predict postoperative remission,
remission at last visit, and resistance to somatostatin receptor ligands (SRL) in patients with …

Machine learning-based clinical outcome prediction in surgery for acromegaly

O Zanier, M Zoli, VE Staartjes, F Guaraldi, S Asioli… - Endocrine, 2022 - Springer
Purpose Biochemical remission (BR), gross total resection (GTR), and intraoperative
cerebrospinal fluid (CSF) leaks are important metrics in transsphenoidal surgery for …

Executive summary of the expert consensus document from the Spanish Society of Neurosurgery and the Spanish Society of Endocrinology and Nutrition: clinical …

M Araujo-Castro, V Rodríguez-Berrocal, E Dios… - … , Diabetes y Nutrición …, 2023 - Elsevier
Pituitary tumors (PT) account for 15% of intracranial tumors affect 10.7%–14.4% of the
population although the incidence of clinically relevant PT is 5.1 cases/100,000 inhabitants …

Postoperative GH and degree of reduction in IGF-1 predicts postoperative hormonal remission in acromegaly

T Cardinal, C Collet, M Wedemeyer… - Frontiers in …, 2021 - frontiersin.org
Purpose Determine predictive factors for long-term remission of acromegaly after
transsphenoidal resection of growth hormone (GH)-secreting pituitary adenomas. Methods …

Endocrine outcomes after pituitary surgery

A Buttan, AN Mamelak - Neurosurgery Clinics, 2019 - neurosurgery.theclinics.com
Removal of tumors in the sellar and parasellar region is a well-established and highly
successful surgical method. Although surgical removal via either the transsphenoidal or the …