Zebrafish neurotransmitter systems as potential pharmacological and toxicological targets

EP Rico, DB Rosemberg, KJ Seibt, KM Capiotti… - Neurotoxicology and …, 2011 - Elsevier
Recent advances in neurobiology have emphasized the study of brain structure and function
and its association with numerous pathological and toxicological events. Neurotransmitters …

Zebrafish model in drug safety assessment

J Kanungo, E Cuevas, SF Ali… - Current pharmaceutical …, 2014 - ingentaconnect.com
Over the past decade, zebrafish are being increasingly used in assessing the effects of
chemical compounds. Especially, the embryos and larvae, due to their microscopically small …

An adenosine receptor for olfaction in fish

N Wakisaka, N Miyasaka, T Koide, M Masuda… - Current biology, 2017 - cell.com
Nucleotides released from food sources into environmental water are supposed to act as
feeding cues for many fish species. However, it remains unknown how fish can sensitively …

[HTML][HTML] Zebrafish models for the functional genomics of neurogenetic disorders

E Kabashi, E Brustein, N Champagne… - Biochimica et Biophysica …, 2011 - Elsevier
In this review, we consider recent work using zebrafish to validate and study the functional
consequences of mutations of human genes implicated in a broad range of degenerative …

[HTML][HTML] Neurochemical and behavioral consequences of ethanol and/or caffeine exposure: Effects in zebrafish and rodents

CL Clayman, VP Connaughton - Current neuropharmacology, 2022 - ncbi.nlm.nih.gov
Zebrafish are increasingly being utilized to model the behavioral and neurochemical effects
of pharmaceuticals and, more recently, pharmaceutical interactions. Zebrafish models of …

Adenosine signaling promotes hematopoietic stem and progenitor cell emergence

L Jing, OJ Tamplin, MJ Chen, Q Deng… - Journal of Experimental …, 2015 - rupress.org
Hematopoietic stem cells (HSCs) emerge from aortic endothelium via the endothelial-to-
hematopoietic transition (EHT). The molecular mechanisms that initiate and regulate EHT …

Environmentally relevant concentration of caffeine—effect on activity and circadian rhythm in wild perch

D Cerveny, P Cisar, T Brodin, ES McCallum… - … Science and Pollution …, 2022 - Springer
We studied the ecological consequences of widespread caffeine contamination by
conducting an experiment focused on changes in the behavioral traits of wild perch (Perca …

Time-dependent interacting effects of caffeine, diazepam, and ethanol on zebrafish behaviour

S Tran, N Fulcher, M Nowicki, P Desai, B Tsang… - Progress in Neuro …, 2017 - Elsevier
Zebrafish have become a popular animal model for behavioural pharmacology due to their
small size, rapid development, and amenability to high throughput behavioural drug …

Similar anxiolytic effects of agonists targeting serotonin 5-HT1A or cannabinoid CB receptors on zebrafish behavior in novel environments

KA Connors, TW Valenti, K Lawless, J Sackerman… - Aquatic toxicology, 2014 - Elsevier
The discovery that selective serotonin reuptake inhibitors (SSRIs) such as fluoxetine are
present and bioaccumulate in aquatic ecosystems have spurred studies of fish serotonin …

Neuromotor activity inhibition in zebrafish early-life stages after exposure to environmental relevant concentrations of caffeine

NO de Farias, T de Sousa Andrade… - … Science and Health …, 2021 - Taylor & Francis
Caffeine (CAF), a neuroactive compound, has been found in surface waters at
concentrations ranging from few nanograms up to micrograms and may induce adverse …