Adaptive immunity is mediated by T‐and B‐cells, which are immune cells capable of
developing pathogen‐specific memory that confers immunological protection. Memory and …

Immunoinformatics involves the application of computational methods to immunological
problems. Prediction of B-and T-cell epitopes has long been the focus of immunoinformatics …

Binding of peptides to major histocompatibility complex (MHC) molecules is the single most
selective step in the recognition of pathogens by the cellular immune system. The human …

A key role in cell-mediated immunity is dedicated to the major histocompatibility complex
(MHC) molecules that bind peptides for presentation on the cell surface. Several in silico …

Background Many processes in molecular biology involve the recognition of short
sequences of nucleic-or amino acids, such as the binding of immunogenic peptides to major …

Motivation: Receptor–ligand interactions play an important role in controlling many
biological systems. One prominent example is the binding of peptides to the major …

Several accurate prediction systems have been developed for prediction of class I major
histocompatibility complex (MHC): peptide binding. Most of these are trained on binding …

In this paper, current prediction methods and algorithms for both T‐and B cell epitopes are
reviewed, and a comprehensive summary of epitope prediction software and databases …

Recognition of peptides bound to major histocompatibility complex (MHC) class I molecules
by T lymphocytes is an essential part of immune surveillance. Each MHC allele has a …

Background Protein antigens and their specific epitopes are formulation targets for epitope-
based vaccines. A number of prediction servers are available for identification of peptides …