Typical migraine is a complex neurological disorder comprised of two main subtypes:
migraine with (MA) and without aura (MO). The disease etiology is still unclear, but family …

Trace amines, including tyramine, octopamine and synephrine, are closely related to classic
biogenic amines. In one study, where these substances were found elevated in plasma of …

This review explores a large series of observations from clinical and experimental studies on
the interactions between migraine and the extrapyramidal system (EPS). A critical appraisal …

Increased negativity of contingent negative variation (CNV) in adult migraineurs is thought to
reflect cortical hyperexcitability. CNV amplitude changes with age in healthy adults …

Background Migraine is a complex neurological disorder characterized by severe recurrent
headache, nausea, vomiting, photophobia, and phonophobia. The frequency and duration …

Migraine is a common debilitating primary headache disorder with significant mental,
physical and social health implications. The brain neurotransmitter 5-hydroxytryptamine (5 …

Patients with chronic daily headaches (CDH) bear similarities to drug or substance abuse
patients, for whom genetic liability loci have been implicated. We reviewed papers dealing …

Platelet serotonin (5-HT) concentrations in a headache-free period during the mid-follicular
phase and the serotonin transporter gene regulatory region polymorphism (5-HTTLPR) were …

Some epidemiological studies have investigated the relationship between genetic
polymorphisms of DRD2, COMT, DBH, and MAO-A and migraine susceptibility, but the …