Insulin-like growth factor (IGF) binding protein-3 (IGFBP-3), one of the six members of the
IGFBP family, is a key protein in the IGF pathway. IGFBP-3 can function in an IGF-dependent …

DNA2 nuclease/helicase is a structure-specific nuclease, 5′-to-3′ helicase, and DNA-
dependent ATPase. It is involved in multiple DNA metabolic pathways, including Okazaki …

During mitosis, transcription is shut off, chromatin condenses, and most transcription factors
(TFs) are reported to be excluded from chromosomes. How do daughter cells re-establish …

2016-01-11 First worldwide family litigation filed litigation Critical https://patents. darts-ip.
com/? family= 49881125&utm_source= google_patent&utm_medium …

Middle East respiratory syndrome coronavirus (MERS-CoV) is a novel human coronavirus
that emerged in 2012, causing severe pneumonia and acute respiratory distress syndrome …

Abstract Background 22q11. 2 deletion syndrome (22q11DS), a copy number variation
(CNV) disorder, occurs in approximately 1: 4000 live births due to a heterozygous …

Nuclear-import receptors (NIRs) bind nuclear-localization signals (NLSs) of protein cargo in
the cytoplasm and transport them into the nucleus. Here, we review advances establishing …

Nucleus, as the machinery for genome transcription, play prominent roles to support the
fundamental cellular functions, the destruction of any of these specific parts would …

NLSdb is a database collecting nuclear export signals (NES) and nuclear localization
signals (NLS) along with experimentally annotated nuclear and non-nuclear proteins. NES …

The nucleus is ultimately the final target for many therapeutics treating various disorders
including cancers, heart dysfunction and brain disorders. Owing to their specialized cell …