Minding the Gap: Exploring Neuroinflammatory and Microglial Sex Differences in Alzheimer's Disease
EG Reed, PR Keller-Norrell - International Journal of Molecular Sciences, 2023 - mdpi.com
Research into Alzheimer's Disease (AD) describes a link between AD and the resident
immune cells of the brain, the microglia. Further, this suspected link is thought to have …
immune cells of the brain, the microglia. Further, this suspected link is thought to have …
Involvement of brain cell phenotypes in stress-vulnerability and resilience
CA Favoretto, M Pagliusi Jr… - Frontiers in Neuroscience, 2023 - frontiersin.org
Stress-related disorders' prevalence is epidemically increasing in modern society, leading to
a severe impact on individuals' well-being and a great economic burden on public …
a severe impact on individuals' well-being and a great economic burden on public …
Tmem119 is involved in bone anabolic effects of PTH through enhanced osteoblastic bone formation in mice
N Kawao, D Matsumura, A Yamada, K Okumoto… - Bone, 2024 - Elsevier
The intermittent administration of parathyroid hormone (PTH) exerts potent bone anabolic
effects, which increase bone mineral density (BMD) and reduce fracture risk in osteoporotic …
effects, which increase bone mineral density (BMD) and reduce fracture risk in osteoporotic …
Microglia undergo sex-dimorphic transcriptional and metabolic rewiring during aging
S Kang, EY Ko, AE Andrews, JE Shin, KJ Nance… - Journal of …, 2024 - Springer
Microglia, the brain's resident macrophages, maintain brain homeostasis and respond to
injury and infection. During aging they undergo functional changes, but the underlying …
injury and infection. During aging they undergo functional changes, but the underlying …
Changes in microglia chromatin accessibility in aged female mice.
VA Ansere, KB Tooley, K Srividya, W Hoolehan… - bioRxiv, 2024 - biorxiv.org
Aged female microglia display a more inflammatory and disease-associated phenotype
compared to age-matched males. Epigenetic mechanisms, such as chromatin accessibility …
compared to age-matched males. Epigenetic mechanisms, such as chromatin accessibility …