Catalytic asymmetric synthesis of atropisomers bearing multiple chiral elements: an emerging field

HH Zhang, TZ Li, SJ Liu, F Shi - Angewandte Chemie, 2024 - Wiley Online Library
With the rapid development of asymmetric catalysis, the demand for the enantioselective
synthesis of complex and diverse molecules with different chiral elements is increasing …

Atroposelective Synthesis of Axially Chiral Diaryl Ethers by N-Heterocyclic-Carbene-Catalyzed Sequentially Desymmetric/Kinetic Resolution Process

L Li, W Ti, T Miao, J Ma, A Lin, Q Chu… - The Journal of Organic …, 2024 - ACS Publications
We describe herein an N-heterocyclic-carbene-catalyzed atroposelective synthesis of axially
chiral diaryl ethers. Through a sequentially enantioselective desymmetric process and a …

[HTML][HTML] Atroposelective synthesis of eight-membered lactam-bridged N-arylindoles via stepwise cut-and-sew strategy

LF Tao, F Huang, X Zhao, L Qian, JY Liao - Cell Reports Physical Science, 2023 - cell.com
The development of efficient processes for the preparation of structurally diverse axially
chiral biaryls has been an important goal in synthetic organic chemistry and asymmetric …

Enantioselective Synthesis of Axially and Centrally Chiral Styrenes via Nickel-Catalyzed Desymmetric Hydrocyanation of Biaryl Dienes

C Li, SZ Cai, J Ye, X Fang - Organic Letters, 2024 - ACS Publications
Herein, a highly regio-, enantio-, and diastereoselective nickel-catalyzed desymmetric
hydrocyanation of biaryl dienes for the simultaneous construction of axial and central …

Catalytic stereodivergent and simultaneous construction of axial and point chirality

WT Wang, S Zhang, W Lin, ZH Luo, D Hu… - Organic Chemistry …, 2024 - pubs.rsc.org
Atropisomers possessing additional stereogenic centres have found wide applications in
various fields; however, the development of catalytic asymmetric reactions for their …