There is a growing body of literature that recognizes the positive effects of exercise on mood
states such as anxiety, stress and depression, through physiological and biochemical …

Both obesity and aging are associated with the development of metabolic diseases such as
type 2 diabetes and cardiovascular disease. Chronic low-grade inflammation of adipose …

The lymphatic system is comprised of a network of vessels interrelated with lymphoid tissue,
which has the holistic function to maintain the local physiologic environment for every cell in …

The pathogenesis of frailty and the role of inflammation is poorly understood. We examined
the evidence considering the relationship between inflammation and frailty through a …

The coronavirus disease 2019 COVID-19 pandemic is rapidly spreading worldwide and is
becoming a major public health crisis. Increasing evidence demonstrates a strong …

Intervertebral disk (IVD) degeneration is a natural progression of the aging process.
Degenerative disk disease (DDD) is a pathologic condition associated with IVD that has …

Abstract Sodium-glucose co-transporter 2 (SGLT2) inhibitors are glucose-lowering drugs
that reduce plasma glucose levels by inhibiting glucose and sodium reabsorption in the …

Chronic low-grade inflammation plays a pivotal role in the pathogenesis of obesity, due to its
associated chronic diseases such as type II diabetes, cardiovascular diseases, pulmonary …

Chronic inflammation, which is called “inflamm-aging”, is characterized by an increased
level of inflammatory cytokines in response to physiological and environmental stressors …

Recent insights into the pathophysiologic underlying mechanisms of obesity have led to the
discovery of several promising drug targets and novel therapeutic strategies to address the …