Basic principles of the virulence of Cryptococcus

O Zaragoza - Virulence, 2019 - Taylor & Francis
Among fungal pathogens, Cryptococcus neoformans has gained great importance among
the scientific community of several reasons. This fungus is the causative agent of …

Regulatory circuitry governing fungal development, drug resistance, and disease

RS Shapiro, N Robbins, LE Cowen - Microbiology and molecular …, 2011 - Am Soc Microbiol
Pathogenic fungi have become a leading cause of human mortality due to the increasing
frequency of fungal infections in immunocompromised populations and the limited …

[图书][B] Cryptococcus neoformans

A Casadevall, JR Perfect - 1998 - Citeseer
MATERIALS AND METHODS Strains and media. C. neoformans var. grubii strains H99 (70),
KN99a (55), KN99 (55), KN99aNAT, and KN99NAT were maintained at 80 C. Cultures were …

The Cryptococcus neoformans capsule: a sword and a shield

TR O'Meara, JA Alspaugh - Clinical microbiology reviews, 2012 - Am Soc Microbiol
The human fungal pathogen Cryptococcus neoformans is characterized by its ability to
induce a distinct polysaccharide capsule in response to a number of host-specific …

Genomic analysis reveals that Pseudomonas aeruginosa virulence is combinatorial

DG Lee, JM Urbach, G Wu, NT Liberati, RL Feinbaum… - Genome biology, 2006 - Springer
Background Pseudomonas aeruginosa is a ubiquitous environmental bacterium and an
important opportunistic human pathogen. Generally, the acquisition of genes in the form of …

Cryptococcal cell morphology affects host cell interactions and pathogenicity

LH Okagaki, AK Strain, JN Nielsen, C Charlier… - PLoS …, 2010 - journals.plos.org
Cryptococcus neoformans is a common life-threatening human fungal pathogen. The size of
cryptococcal cells is typically 5 to 10 µm. Cell enlargement was observed in vivo, producing …

Genomic Islands in the Pathogenic Filamentous Fungus Aspergillus fumigatus

ND Fedorova, N Khaldi, VS Joardar, R Maiti… - PLoS …, 2008 - journals.plos.org
We present the genome sequences of a new clinical isolate of the important human
pathogen, Aspergillus fumigatus, A1163, and two closely related but rarely pathogenic …

Impact of melanin on microbial virulence and clinical resistance to antimicrobial compounds

JD Nosanchuk, A Casadevall - Antimicrobial agents and …, 2006 - Am Soc Microbiol
Melanins are negatively charged, hydrophobic pigments of high molecular weight (54, 88,
95, 139) that are composed of polymerized phenolic and/or indolic compounds (Fig. 1)(45 …

Galleria mellonella as a Model System To Study Cryptococcus neoformans Pathogenesis

E Mylonakis, R Moreno, JB El Khoury… - Infection and …, 2005 - Am Soc Microbiol
Evaluation of Cryptococcus neoformans virulence in a number of nonmammalian hosts
suggests that C. neoformans is a nonspecific pathogen. We used the killing of Galleria …

The Biology of the Cryptococcus neoformans Species Complex

X Lin, J Heitman - Annu. Rev. Microbiol., 2006 - annualreviews.org
Cryptococcus neoformans is a major cause of fungal meningoencephalitis in
immunocompromised patients. Despite recent advances in the genetics and molecular …