In the search for optimal platforms for protein expression and secretion, filamentous fungi in
principle provide some of the best microbial cell factories. They are inherently endowed with …

Filamentous fungi can produce many valuable secondary metabolites; among these fungi,
endophytic fungi play an ecological role in mutualistic symbiosis with plants, including …

Aspergillus niger is an important industrial workhorse for the biomanufacturing of organic
acids, proteins, etc. Well-controlled genetic regulatory elements, including promoters, are …

The high cost and process complexity limit the enzymatic extraction of β-glucan. In this study,
β-glucan was extracted from oat bran in a two-step enzymatic pathway using a recombinant …

Background Filamentous fungi are extensively exploited as important enzyme producers
due to the superior secretory capability. However, the complexity of their secretomes greatly …

The fungus Trichoderma reesei is a powerful host for secreted production of proteins. The
promoter of cdna1 gene, which encodes a small basic protein of unknown function and high …

Ganoderic acids (GAs), a group of highly oxygenated lanostane-type triterpenoids from the
traditional Chinese medicinal mushroom Ganoderma lucidum, possessed significant …

In this study, the acidic lipase from Aspergillus niger (ANL) was homologously expressed in
A. niger. The expression of ANL was significantly improved by the expression of the native …

Genetic engineering is one of the most effective methods to obtain fungus strains with
desirable traits. However, in some filamentous fungi, targeted gene deletion transformant …

For more than a thousand years, Aspergillus oryzae has been used in traditional culinary
industries, including for food fermentation, brewing, and flavoring. In recent years, A. oryzae …