Mycobacterium tuberculosis (Mtb) infection is a major international public health problem.
One‐third of the world′ s population is thought to have latent tuberculosis, a condition …

Natural killer (NK) cells are important in the host resistance to viral infections. They are
among the first cells to sense the release of proinflammatory cytokines, as well as the …

With the emerging obesity pandemic, identifying those who appear to be protected from
adverse consequences such as type 2 diabetes and certain malignancies will become …

Dengue virus (DV) and West Nile virus (WNV) have become a global concern due to their
widespread distribution and their ability to cause a variety of human diseases. Antiviral …

Natural killer cells are important in innate defense against viral infections. The interplay
between stimulatory and inhibitory natural killer cell receptors and their corresponding …

Here I present the idea that the immune system uses a computational strategy to carry out its
many functions in protecting and maintaining the body. Along the way, I define the concepts …

Natural killer (NK) cells are innate immune cells that mediate resistance against viruses and
tumors. They express multiple activating receptors that couple to immunoreceptor tyrosine …

The Bacille Calmette-Guérin or BCG vaccine, the only vaccine available against
Mycobacterium tuberculosis can induce a marked Th1 polarization of T-cells, characterized …

Human cytomegalovirus (hCMV) infection is usually asymptomatic but may cause disease in
immunocompromised hosts. It has been reported that hCMV infection may shape the NK cell …

Viruses as obligate intracellular parasites require their host to replicate them and to facilitate
their spread to others. In humans, viral infections are rarely lethal, even if they are highly …