Stereotactic electroencephalogaphy (sEEG) utilizes localized, penetrating depth electrodes
to measure electrophysiological brain activity. It is most commonly used in the identification …

Recent years have seen fast advances in neural recording circuits and systems as they offer
a promising way to investigate real-time brain monitoring and the closed-loop modulation of …

Background The progress in microtechnology has enabled an exponential trend in the
number of neurons that can be simultaneously recorded. The data bandwidth requirement is …

Large-scale in vivo electrophysiology requires tools that enable simultaneous recording of
multiple brain regions at single-neuron level. This calls for the design of more compact …

Biomedical circuits and systems are heading toward a multidisciplinary race in two main
directions. On the one hand, advanced smart medical devices must be built to improve …

Objective. Longitudinal observation of single unit neural activity from large numbers of
cortical neurons in awake and mobile animals is often a vital step in studying neural network …

Neuromodulation technologies are progressing from pacemaking and sensory operations to
full closed-loop control. In particular, optogenetics-the genetic modification of light sensitivity …

Objective. Various on-workstation neural-spike-based brain machine interface (BMI)
systems have reached the point of in-human trials, but on-node and on-implant BMI systems …

We present a fully implantable neural recording IC with a spike-driven data compression
scheme to improve the power efficiency and preserve crucial data for monitoring brain …

There is an increasing demand for real-time neural signal monitoring from a large number of
electrodes to provide adequate spatial and temporal resolution for high-density brain neural …