Cardiovascular disease is the leading cause of death in women. Decades of grassroots
campaigns have helped to raise awareness about the impact of cardiovascular disease in …

Mitral annular calcification (MAC) is a common and challenging pathologic condition,
especially in the context of an aging society. Surgical mitral valve intervention in patients …

Abstract Background The MITRAL (Mitral Implantation of Transcatheter Valves) trial is the
first prospective study for valve-in-mitral annular calcification (ViMAC), mitral valve-in-ring …

Valvular heart disease is common and its prevalence is rapidly increasing worldwide.
Effective medical therapies are insufficient and treatment was historically limited to the …

This review discusses recent advancements in the field of valvular heart disease. Topics
covered include recognition of the impact of atrial fibrillation on development and …

Abstract Background The MITRAL (Mitral Implantation of Transcatheter Valves) trial is the
first prospective trial to evaluate the safety and feasibility of balloon-expandable aortic …

Mitral annular calcification (MAC) refers to calcium deposition in the fibrous skeleton of the
mitral valve. It has many cardiovascular associations, including mitral valve dysfunction …

An increasing number of patients with mitral valve disease are high risk for surgery and in
need of less invasive treatments including transcatheter mitral valve replacement (TMVR) …

Background A significant number of patients with severe mitral regurgitation (MR) are not
suitable for either surgical or transcatheter edge-to-edge repair because of high surgical risk …

Mitral regurgitation is the second-most frequent valvular heart disease in Europe and it is
associated with high morbidity and mortality. Recognition of MR should encourage the …