Asthma treatment goals currently focus on symptom and exacerbation control rather than
remission. Remission is not identical to cure, but is a step closer. This review considers the …

The Global Initiative for Asthma (GINA) was launched in 1993 under the auspices of the
National Heart, Lung, and Blood Institute, National Institutes of Health, USA, and the World …

Background Overuse of short-acting β 2-agonists (SABA) may indicate poor asthma control
and adverse health outcomes. Contemporary population-based data on use, risk factors and …

Bronchiectasis, a progressive chronic airway disease, is characterized by microbial
colonization and infection. We present an approach to the multi-biome that integrates …

Admixed populations are routinely excluded from genomic studies due to concerns over
population structure. Here, we present a statistical framework and software package, Tractor …

Rhinoviruses and allergens, such as house dust mite are major agents responsible for
asthma exacerbations. The influence of pre-existing airway inflammation on the infection …

Control theory and other frameworks for understanding self-regulation suggest that
monitoring goal progress is a crucial process that intervenes between setting and attaining a …

The important life-supporting role of hydrogen sulfide (H2S) has evolved from bacteria to
plants, invertebrates, vertebrates, and finally to mammals. Over the centuries, however, H2S …

Animal models remain invaluable for study of respiratory diseases, however, translation of
data generated in genetically homogeneous animals housed in a clean and well-controlled …

The benefits of drug therapy for asthma have been well established, but adherence to
treatment is poor, and this might be associated with an increased risk of asthma …