Agmatine, an endogenous polyamine derived from L-arginine, elicits tremendous
multimodal neuromodulant properties. Alterations in agmatinergic signalling are closely …

Agmatine, the decarboxylation product of arginine, was largely neglected as an important
player in mammalian metabolism until the mid-1990s, when it was re-discovered as an …

Abstract Ethnopharmacological relevance Gastrodia elata Blume (GE) is a Chinese
medicinal herb commonly used to treat central nervous system-related diseases, including …

Sphingosine receptors (S1PRs) are implicated in the progression of neurodegenerative
diseases and metabolic disorders like obesity and type 2 diabetes (T2D). The link between …

People that committed suicide were reported to have enhanced levels of gene transcripts for
synaptic proteins in their prefrontal cortex (PFC). Given the close association of suicide with …

Chronic maternal ethanol exposure leads to poor intelligence, impaired cognition and array
of neurological symptoms in offsprings and commonly referred as fetal alcohol spectrum …

Epidemiological studies indicated that mood disorders like depression and anxiety are
highly prevalent in type-II diabetes mellitus (T2DM). However, the neurobiological …

Ferulic acid is a hydroxycinnamic acid that widely presents in plant cell wall components. It
has been demonstrated that ferulic acid can reverse depressive-like behaviors in both …

The central nervous system (CNS) is the most injury-prone part of the mammalian body. Any
acute or chronic, central or peripheral neurological disorder is related to abnormal …

Agmatine is a neuromodulator that regulates multiple neurotransmitters and signaling
pathways. Several studies have focused on elucidating the mechanisms underlying the …