Identification of promising compounds from curry tree with cyclooxygenase inhibitory potential using a combination of machine learning, molecular docking, dynamics …

PN Pandya, SP Kumar, K Bhadresha… - Molecular …, 2020 - Taylor & Francis
ABSTRACT Murraya koenigii (Linn.) Spreng, commonly known as curry leaf tree, is popular
as a condiment and spice among Asian countries. Ethnobotanical studies suggest that …

Mexican grasshopper (Sphenarium purpurascens) as source of high protein flour: Techno-functional characterization, and in silico and in vitro biological potential

VM Villaseñor, JN Enriquez-Vara, JE Urías-Silva… - Food Research …, 2022 - Elsevier
The aim of this work was to evaluate the techno-functional properties of Mexican
grasshopper flour with different thermal pretreatments, as well as to assess the anti …

Cyclooxygenase-2 (COX-2)-a therapeutic target in liver cancer?

M Breinig, P Schirmacher… - Current pharmaceutical …, 2007 - ingentaconnect.com
Targeting COX-2, a key-enzyme of the prostaglandin metabolism, for the treatment of cancer
has been in the focus of researchers for about a decade. However, only recently has this …

[HTML][HTML] A systematic review of the cyclooxygenase-2 (COX-2) expression in rectal cancer patients treated with preoperative radiotherapy or radiochemotherapy

M Berbecka, A Forma, J Baj… - Journal of Clinical …, 2021 - mdpi.com
The main objective of this systematic review is to investigate the expression level of the
cyclooxygenase-2 (COX-2) in rectal cancer treated with either preoperative radiotherapy or …

A general method for the synthesis of aryl [11C] methylsulfones: potential PET probes for imaging cyclooxygenase-2 expression

VJ Majo, J Prabhakaran, NR Simpson… - Bioorganic & medicinal …, 2005 - Elsevier
A general one-pot method has been developed for the conversion of an aryl thiol moiety
masked as the butyrate ester to the corresponding 11C-labeled methylsulfone group. The …

Similar antineoplastic effects of nimesulide, a selective COX-2 inhibitor, and prostaglandin E1 on B16-F10 murine melanoma cells

C Tabolacci, A Lentini, B Provenzano… - Melanoma …, 2010 - journals.lww.com
There is now increasing evidence that a constitutive expression of cyclooxygenase 2 (COX-
2) plays a role in the development and progression of malignant ectodermal tumours. In this …

Chemoprevention of colorectal cancer: ready for routine use?

N Arber, B Levin - Current Topics in Medicinal Chemistry, 2005 - ingentaconnect.com
In the third millennium preventive medicine is becoming a corner stone in our concept of
health. Colorectal cancer (CRC) prevention, in particular, has become an important goal for …

Cyclooxygenase-2 dependent and independent antitumor effects induced by celecoxib in urinary bladder cancer cells

D Dhawan, AB Jeffreys, R Zheng, JC Stewart… - Molecular Cancer …, 2008 - AACR
Transitional cell carcinoma of the urinary bladder is the second most common genitourinary
malignancy in people in the United States. Cyclooxygenase-2 (COX-2) is overexpressed in …

Cyclooxygenase-2 (COX-2) expression in human endometrial carcinoma and precursor lesions and its possible use in cancer chemoprevention and therapy

A Nasir, D Boulware, HE Kaiser, JM Lancaster… - in vivo, 2007 - iv.iiarjournals.org
In recent years, the design of new antineoplastic agents that can halt the progression of
human malignancies with minimal systemic damage has been at the forefront of cancer …

Prostaglandin E2 as a therapeutic target in bladder cancer: From basic science to clinical trials

BL Woolbright, CC Pilbeam, JA Taylor III - Prostaglandins & Other Lipid …, 2020 - Elsevier
Bladder cancer (BCa) is a common solid tumor marked by high rates of recurrence,
especially in non-muscle invasive disease. Prostaglandin E 2 (PGE 2) is a ubiquitously …