The MYC transcription factor, encoded by the c‐MYC proto‐oncogene, is activated by
growth‐promoting signals, and is a key regulator of biosynthetic and metabolic pathways …

Cancer is a societal burden demanding innovative approaches. A major problem with the
conventional chemotherapeutic agents is their strong toxicity and other side effects due to …

The tetrasubstituted naphthalene diimide compound QN-302 binds to G-quadruplex (G4)
DNA structures. It shows high potency in pancreatic ductal adenocarcinoma (PDAC) cells …

G-quadruplex, a structurally unique structure in nucleic acids present all throughout the
human genome, has sparked great attention in therapeutic investigations. Targeting G …

The formation of G-quadruplex structures (G4s) in vitro from guanine (G)-rich nucleic acid
sequences of DNA and RNA stabilized with monovalent cations, typically K+ and Na+, under …

Holliday 4-way junctions are key to important biological DNA processes (insertion,
recombination, and repair) and are dynamic structures that adopt either open or closed …

DNA G-quadruplexes (G4s) have been identified as important biological targets for
transcriptional, translational, and epigenetic regulation. The stabilisation of G4s with small …

In recent years, G-quadruplexes (G4s), types of noncanonical four-stranded nucleic acid
structures, have been identified in many viruses that threaten human health, such as HIV …

G-quadruplexes turned out to be important targets for the development of novel targeted
anticancer/antiviral therapies. More than 3000 G-quadruplex small-molecule ligands have …

Metallo-phthalocyanines (MPc) are common photosensitizers with ideal photophysical and
photochemical properties. Also, these molecules have shown to interact with non-canonical …