For many years, nanocarriers have been investigated to modify pharmacokinetics and
biodistribution of various active molecules. In the cancer domain, one of the biggest …

Hepatocellular carcinoma (HCC) is one of the most lethal cancers worldwide. Surgical
resection and liver transplantation are still the best options for treatment. Nevertheless, as …

ABCB6 is a member of the adenosine triphosphate (ATP)-binding cassette family of
transporter proteins that is increasingly recognized as a relevant physiological and …

This unit provides both a theoretical and a practical background to all the techniques
associated with the application of differential and density gradient centrifugation for the …

The human ATP-binding cassette (ABC) transporter ABCB6 is involved in haem-precursor
transport across the mitochondrial membrane. The crystal structure of its nucleotide-binding …

ATP‐binding cassette (ABC) transporters are implicated in a diverse range of physiological
and pathophysiological processes, such as cholesterol and lipid transportation and …

Background Members of the HMT-1 (h eavy m etal t olerance factor 1) subfamily of the ATP-
binding cassette (ABC) transporter superfamily detoxify heavy metals and have unique …

As a component of heme and iron–sulfur cluster-containing proteins, iron is essential for
oxygen transport, cellular respiration, DNA synthesis, and numerous other biochemical …

ATP-binding cassette (ABC) transporters are one of the largest families of membrane
proteins in prokaryotic organisms. Much is now understood about the structure of these …

Quantifying the protein levels of drug transporters in plasma membrane fraction helps
elucidate the function of these transporters. In this study, we conducted a proteomic …