VEGF promotes tendon regeneration of aged rats by inhibiting adipogenic differentiation of tendon stem/progenitor cells and promoting vascularization

F Lai, J Wang, H Tang, P Huang, J Liu, G He… - The FASEB …, 2022 - Wiley Online Library
Studies have shown that the stem cell microenvironment is a key factor for stem cell
maintenance or differentiation. In this study, we compared the expression of 23 cytokines …

[HTML][HTML] From the perspective of embryonic tendon development: various cells applied to tendon tissue engineering

F Qi, Z Deng, Y Ma, S Wang, C Liu, F Lyu… - Annals of …, 2020 - ncbi.nlm.nih.gov
There is a high risk of injury from damage to the force-bearing tissue of the tendon. Due to its
poor self-healing ability, clinical interventions for tendon injuries are limited and yield …

[HTML][HTML] Bioactive nanostructured scaffold-based approach for tendon and ligament tissue engineering

DT Govindaraju, CH Chen, KT Shalumon, HH Kao… - Nanomaterials, 2023 - mdpi.com
An effective therapeutic strategy to treat tendon or ligament injury continues to be a clinical
challenge due to the limited natural healing capacity of these tissues. Furthermore, the …

Tenocyte-imprinted substrate: A topography-based inducer for tenogenic differentiation in adipose tissue-derived mesenchymal stem cells

SMA Haramshahi, S Bonakdar… - Biomedical …, 2020 - iopscience.iop.org
Tendon tissue engineering based on stem cell differentiation has attracted a great deal of
attention in recent years. Previous studies have examined the effect of cell-imprinted …

[HTML][HTML] Tissue engineering strategies for the treatment of tendon injuries: a systematic review and meta-analysis of animal models

D González-Quevedo, I Martínez-Medina… - Bone & joint …, 2018 - boneandjoint.org.uk
Objectives Recently, the field of tissue engineering has made numerous advances towards
achieving artificial tendon substitutes with excellent mechanical and histological properties …

The use of cocultured mesenchymal stem cells with tendon-derived stem cells as a better cell source for tendon repair

T Wu, Y Liu, B Wang, Y Sun, J Xu… - … Engineering Part A, 2016 - liebertpub.com
The management of tendon tissue injury presents a significant clinical challenge due to the
unique properties of tendons. Cell-based therapy provides a new alternative for …

HMGB1: a potential new target for tendinopathy treatment

P Lu, Y Li, G Dai, Y Zhang, L Shi, M Zhang… - Connective Tissue …, 2023 - Taylor & Francis
Tendinopathy describes a complex pathology of the tendon characterized by abnormalities
in the microstructure, composition, and cellularity of the tendon, leading to pain, limitation of …

[HTML][HTML] Characterization and comparison of post-natal rat Achilles tendon-derived stem cells at different development stages

J Chen, W Zhang, Z Liu, T Zhu, W Shen, J Ran… - Scientific reports, 2016 - nature.com
Tendon stem/progenitor cells (TSPCs) are a potential cell source for tendon tissue
engineering. The striking morphological and structural changes of tendon tissue during …

[HTML][HTML] A comparison of the stem cell characteristics of murine tenocytes and tendon-derived stem cells

KJ Lee, PD Clegg, EJ Comerford… - BMC Musculoskeletal …, 2018 - Springer
Tendon is a commonly injured soft musculoskeletal tissue, however, poor healing potential
and ineffective treatment strategies result in persistent injuries and tissue that is unable to …

Exploring stem cells and inflammation in tendon repair and regeneration

A Vinhas, MT Rodrigues, ME Gomes - Cell Biology and Translational …, 2018 - Springer
Tendon injuries are frequent and are responsible for substantial morbidity both in sports and
in the workplace. Despite the endogenous mechanisms of tendon repair and regeneration …