Radiotherapy combined with immunotherapy: the dawn of cancer treatment
Z Zhang, X Liu, D Chen, J Yu - Signal transduction and targeted …, 2022 - nature.com
Radiotherapy (RT) is delivered for purposes of local control, but can also exert systemic
effect on remote and non-irradiated tumor deposits, which is called abscopal effect. The view …
effect on remote and non-irradiated tumor deposits, which is called abscopal effect. The view …
Radiotherapy and immunotherapy: a beneficial liaison?
Investigations into the interaction between radiotherapy and the host immune system have
uncovered new mechanisms that can potentially be exploited to improve the efficacy of …
uncovered new mechanisms that can potentially be exploited to improve the efficacy of …
Mild magnetic hyperthermia-activated innate immunity for liver cancer therapy
J Pan, Y Xu, Q Wu, P Hu, J Shi - Journal of the American Chemical …, 2021 - ACS Publications
Magnetic hyperthermia therapy (MHT) is noninvasive and features excellent tissue
penetration for deep-seated tumors, but unfortunately, it suffers the low therapeutic efficacy …
penetration for deep-seated tumors, but unfortunately, it suffers the low therapeutic efficacy …
Abscopal effect of radiotherapy combined with immune checkpoint inhibitors
Y Liu, Y Dong, L Kong, F Shi, H Zhu, J Yu - Journal of hematology & …, 2018 - Springer
Radiotherapy (RT) is used routinely as a standard treatment for more than 50% of patients
with malignant tumors. The abscopal effect induced by local RT, which is considered as a …
with malignant tumors. The abscopal effect induced by local RT, which is considered as a …
Radiation and checkpoint blockade immunotherapy: radiosensitisation and potential mechanisms of synergy
Checkpoint blockade immunotherapy has received mainstream attention as a result of
striking and durable clinical responses in some patients with metastatic disease and a …
striking and durable clinical responses in some patients with metastatic disease and a …
Acquired resistance to fractionated radiotherapy can be overcome by concurrent PD-L1 blockade
SJ Dovedi, AL Adlard, G Lipowska-Bhalla, C McKenna… - Cancer research, 2014 - AACR
Radiotherapy is a major part in the treatment of most common cancers, but many patients
experience local recurrence with metastatic disease. In evaluating response biomarkers, we …
experience local recurrence with metastatic disease. In evaluating response biomarkers, we …
Time to abandon single-site irradiation for inducing abscopal effects
ED Brooks, JY Chang - Nature reviews Clinical oncology, 2019 - nature.com
Considerable interest is being directed toward combining immune-checkpoint inhibition (ICI)
with radiotherapy to improve response rates to ICI, which have been disappointingly low at …
with radiotherapy to improve response rates to ICI, which have been disappointingly low at …
Combining radiotherapy and cancer immunotherapy: a paradigm shift
SC Formenti, S Demaria - JNCI: Journal of the National Cancer …, 2013 - academic.oup.com
The therapeutic application of ionizing radiation has been largely based on its cytocidal
power combined with the ability to selectively target tumors. Radiotherapy effects on survival …
power combined with the ability to selectively target tumors. Radiotherapy effects on survival …
[HTML][HTML] Immunomodulation of the tumor microenvironment: turn foe into friend
H Locy, S De Mey, W De Mey, M De Ridder… - Frontiers in …, 2018 - frontiersin.org
Immunotherapy, where the patient's own immune system is exploited to eliminate tumor
cells, has become one of the most prominent new cancer treatment options in the last …
cells, has become one of the most prominent new cancer treatment options in the last …
[HTML][HTML] Combining immune checkpoint inhibitors with conventional cancer therapy
Y Yan, AB Kumar, H Finnes, SN Markovic… - Frontiers in …, 2018 - frontiersin.org
Immune checkpoint inhibitors (ICIs) have recently revolutionized cancer treatment, providing
unprecedented clinical benefits. However, primary or acquired therapy resistance can affect …
unprecedented clinical benefits. However, primary or acquired therapy resistance can affect …