Influenza viruses replicate within the nucleus of the host cell. This uncommon RNA virus trait
provides influenza with the advantage of access to the nuclear machinery during replication …

The nucleoplasm is not homogenous; it consists of many types of nuclear bodies, also
known as nuclear domains or nuclear subcompartments. These self-organizing structures …

Signal peptides (SP) are short peptides located in the N-terminal of proteins, carrying
information for protein secretion. They are ubiquitous to all prokaryotes and eukaryotes. SPs …

The genomes of large multicellular eukaryotes are mostly comprised of non-protein coding
DNA. Although there has been much agreement that a small fraction of these genomes has …

The intron has been a big biological mystery since it was first discovered in several aspects.
First, all of the completely sequenced eukaryotes harbor introns in the genomic structure …

A comprehensive understanding of RNA structure will provide fundamental insights into the
cellular function of both coding and non-coding RNAs. Although many RNA structures have …

The structures of RNA molecules are often important for their function and regulation,,,,,, yet
there are no experimental techniques for genome-scale measurement of RNA structure …

The muscleblind-like (Mbnl) family of RNA-binding proteins plays important roles in muscle
and eye development and in myotonic dystrophy (DM), in which expanded CUG or CCUG …

Abstract mRNA is packaged into ribonucleoprotein particles called mRNPs. A multitude of
RNA-binding proteins as well as a host of associated proteins participate in the fate of …

With the advent of deep sequencing technologies and the ability to analyze whole genome
sequences and transcriptomes, there has been a growing interest in exploring putative …