The brain is supplied by an elaborate vascular network that originates extracranially and
reaches deep into the brain. The concept of the neurovascular unit provides a useful …

Brain function critically depends on a close matching between metabolic demands,
appropriate delivery of oxygen and nutrients, and removal of cellular waste. This matching …

The concept of the neurovascular unit (NVU), formalized at the 2001 Stroke Progress
Review Group meeting of the National Institute of Neurological Disorders and Stroke …

Cerebral blood flow (CBF) regulation is essential for normal brain function. The mammalian
brain has evolved a unique mechanism for CBF control known as neurovascular coupling …

The science of emotion has been using folk psychology categories derived from philosophy
to search for the brain basis of emotion. The last two decades of neuroscience research …

Background Synapse damage and loss are fundamental to the pathophysiology of
Alzheimer's disease (AD) and lead to reduced cognitive function. The goal of this review is to …

In this paper, we integrate recent theoretical and empirical developments in predictive
coding and active inference accounts of interoception (including the Embodied Predictive …

Increases in brain blood flow, evoked by neuronal activity, power neural computation and
form the basis of BOLD (blood-oxygen-level-dependent) functional imaging. Whether blood …

The precise regulation of cerebral blood flow is critical for normal brain function, and its
disruption underlies many neuropathologies. The extent to which smooth muscle-covered …

Vascular cognitive impairment defines alterations in cognition, ranging from subtle deficits to
full-blown dementia, attributable to cerebrovascular causes. Often coexisting with …