The epidemic nature of diabetes mellitus in different regions is reviewed. The Middle East
and North Africa region has the highest prevalence of diabetes in adults (10.9%) whereas …

Type 1 diabetes mellitus (T1DM) is an endocrine disorder in which pancreatic β cells stop
producing insulin, typically due to autoimmune destruction. This results in hyperglycemia …

Background In persons with type 1 diabetes and high glycated hemoglobin levels, the
benefits of intermittently scanned continuous glucose monitoring with optional alarms for …

Background The pandemic of physical inactivity is associated with a range of chronic
diseases and early deaths. Despite the well documented disease burden, the economic …

Aims/hypothesis Data on type 1 diabetes incidence and prevalence are limited, particularly
for adults. This study aims to estimate global numbers of incident and prevalent cases of …

Hybrid closed‐loop systems are characterized by the coexistence of algorithm‐driven
automated insulin delivery combined with manual mealtime boluses. Used correctly, these …

Melatonin modulates a wide range of physiological functions with pleiotropic effects on the
immune system. Despite the large number of reports implicating melatonin as an …

Diabetic foot ulcers (DFUs) are a chronic, non-healing complication of diabetes that lead to
high hospital costs and, in extreme cases, to amputation. Diabetic neuropathy, peripheral …

In the tissue engineering (TE) paradigm, engineering and life sciences tools are combined
to develop bioartificial substitutes for organs and tissues, which can in turn be applied in …

Macrophages and neutrophils are key components involved in the regulation of numerous
chronic inflammatory diseases, infectious disorders, and especially certain autoimmune …