Bacteria of the genus Staphylococcus are a prominent cause of acute and chronic infections.
The ability of the staphylococci to establish biofilms has been linked to the persistence of …

The development of bacterial resistance to currently available antibacterial agents is a
growing global health problem. Of particular concern are infections caused by multidrug …

TO THE EDITOR: In his review of linezolid, Moellering (1) appropriately calls for clinical trials
comparing the efficacy and safety of linezolid with those of other new drugs active against …

Many common gram-positive pathogens (eg, Staphylococcus aureus, Enterococcus spp,
and Streptococcus pneumoniae) have become increasingly resistant to antimicrobial …

The emergence of new antibiotic-resistance in the significant Gram-positive pathogens in
the last decade created a substantial medical need for new classes of antibacterial agents …

The judicious use of antibiotics to combat infections in children relies upon appropriate
selection of an agent, dose and duration to maximise efficacy and to minimise toxicity …

The oxazolidinones represent the first truly new class of antibacterial agents to reach the
marketplace in several decades. They have a unique mechanism of action involving …

Endocarditis Caused by Methicillin-Resistant Staphylococcus aureus: Treatment Failure
with Linezolid | Clinical Infectious Diseases | Oxford Academic Skip to Main Content …

S. aureus infective endocarditis (SAIE) is a serious infection associated with considerable
morbidity and mortality. There is evidence that the incidence of SAIE is increasing. As its …

The efficacies of orally (po) dosed linezolid and intravenously (iv) dosed vancomycin against
methicillin-resistant Staphylococcus aureus (MRSA) in rabbits with experimental aortic-valve …