Immunity, endothelial injury and complement-induced coagulopathy in COVID-19

L Perico, A Benigni, F Casiraghi, LFP Ng… - Nature Reviews …, 2021 - nature.com
In December 2019, a novel coronavirus was isolated from the respiratory epithelium of
patients with unexplained pneumonia in Wuhan, China. This pathogen, named severe acute …

D-dimer level in COVID-19 infection: a systematic review

M Rostami, H Mansouritorghabeh - Expert review of hematology, 2020 - Taylor & Francis
Introduction COVID-19 disease has spread worldwide from December 2019 to the present
day; the early stage of this disease can be associated with high D-dimer, prolonged PT, and …

COVID-19: coagulopathy, risk of thrombosis, and the rationale for anticoagulation

W Miesbach, M Makris - Clinical and applied thrombosis …, 2020 - journals.sagepub.com
The novel coronavirus infection (COVID-19) is caused by the new coronavirus SARS-CoV-2
and is characterized by an exaggerated inflammatory response that can lead to severe …

COVID-19 length of hospital stay: a systematic review and data synthesis

EM Rees, ES Nightingale, Y Jafari, NR Waterlow… - BMC medicine, 2020 - Springer
Background The COVID-19 pandemic has placed an unprecedented strain on health
systems, with rapidly increasing demand for healthcare in hospitals and intensive care units …

Biomarkers in COVID-19: an up-to-date review

M Samprathi, M Jayashree - Frontiers in pediatrics, 2021 - frontiersin.org
The ongoing pandemic of coronavirus disease 2019 (COVID-19) poses several challenges
to clinicians. Timely diagnosis and hospitalization, risk stratification, effective utilization of …

[HTML][HTML] IL-6: Relevance for immunopathology of SARS-CoV-2

EO Gubernatorova, EA Gorshkova, AI Polinova… - Cytokine & growth factor …, 2020 - Elsevier
COVID-19 mortality is strongly associated with the development of severe pneumonia and
acute respiratory distress syndrome with the worst outcome resulting in cytokine release …

COVID-19 and cancer: a comprehensive review

R Gosain, Y Abdou, A Singh, N Rana, I Puzanov… - Current oncology …, 2020 - Springer
Abstract Purpose of Review The outbreak of the novel coronavirus disease 2019 (COVID-
19) has emerged to be the biggest global health threat worldwide, which has now infected …

Effective inhibition of SARS-CoV-2 entry by heparin and enoxaparin derivatives

R Tandon, JS Sharp, F Zhang, VH Pomin… - Journal of …, 2021 - Am Soc Microbiol
Severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) has caused a
pandemic of historic proportions and continues to spread globally, with enormous …

Heparin as a therapy for COVID-19: current evidence and future possibilities

JA Hippensteel, WB LaRiviere… - … of Physiology-Lung …, 2020 - journals.physiology.org
Coronavirus disease 2019 (COVID-19), the clinical syndrome associated with infection by
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has impacted nearly every …

Weathering the COVID-19 storm: Lessons from hematologic cytokine syndromes

JT England, A Abdulla, CM Biggs, AYY Lee, KA Hay… - Blood Reviews, 2021 - Elsevier
A subset of patients with severe COVID-19 develop profound inflammation and multi-organ
dysfunction consistent with a “Cytokine Storm Syndrome”(CSS). In this review we compare …