Reviewing explore/exploit decision-making as a transdiagnostic target for psychosis, depression, and anxiety

A Lloyd, JP Roiser, S Skeen, Z Freeman… - Cognitive, Affective, & …, 2024 - Springer
In many everyday decisions, individuals choose between trialling something novel or
something they know well. Deciding when to try a new option or stick with an option that is …

Neural evidence of switch processes during semantic and phonetic foraging in human memory

NB Lundin, JW Brown, BT Johns… - Proceedings of the …, 2023 - National Acad Sciences
Humans may retrieve words from memory by exploring and exploiting in “semantic space”
similar to how nonhuman animals forage for resources in physical space. This has been …

[HTML][HTML] Maternal selenium dietary supplementation alters sociability and reinforcement learning deficits induced by in utero exposure to maternal immune activation …

B Gillespie, MJ Houghton, K Ganio, CA McDevitt… - Brain, Behavior, and …, 2024 - Elsevier
Maternal immune activation (MIA) during pregnancy increases the risk for the unborn foetus
to develop neurodevelopmental conditions such as autism spectrum disorder and …

Sex differences in patch-leaving foraging decisions in rats

M Garcia, S Gupta… - Oxford Open Neuroscience, 2023 - academic.oup.com
The ubiquity, importance, and sophistication of foraging behavior makes it an ideal platform
for studying naturalistic decision making in animals. We developed a spatial patch-foraging …

[HTML][HTML] Foraging Under Uncertainty Follows the Marginal Value Theorem with Bayesian Updating of Environment Representations

J Webb, P Steffan, BY Hayden, D Lee, C Kemere… - bioRxiv, 2024 - ncbi.nlm.nih.gov
Foraging theory has been a remarkably successful approach to understanding the behavior
of animals in many contexts. In patch-based foraging contexts, the marginal value theorem …

Meta-Analysis Reveals That Explore-Exploit Decisions are Dissociable by Activation in the Dorsal Lateral Prefrontal Cortex and the Anterior Cingulate Cortex

D Sazhin, A Dachs, DV Smith - bioRxiv, 2023 - biorxiv.org
Explore-exploit research has challenges in generalizability due to a limited theoretical basis
of exploration and exploitation. Neuroimaging can help identify whether explore-exploit …

A Causal Role of the Right Dorsolateral Prefrontal Cortex in Random Exploration

A Toghi, M Chizari, R Khosrowabadi - bioRxiv, 2024 - biorxiv.org
Our brain faces the dilemma of exploiting familiar options to gain immediate rewards or
exploring new options to increase probable future rewards, in many real-life decisions, and …

Basal Ganglia Stimulation Ameliorates Schizophrenia Exploration Anomalies

N Asch, N Rahamim, U Werner-Reiss, Z Israel… - bioRxiv, 2023 - biorxiv.org
Any learning agent must balance between exploiting its knowledge and exploring new
alternatives. Schizophrenia patients are known to have maladaptive exploration-exploitation …

Identifying mechanistic pathways to rigidity associated with Obsessive-Compulsive Personality Disorder traits using a novel decision-making paradigm

HL Heintz - 2024 - scholarscompass.vcu.edu
Cognitive and behavioral rigidity is observed across several mental disorders and is a
defining characteristic of Obsessive-Compulsive Personality Disorder (OCPD), a highly …

The impact of maternal immune activation on GABAergic interneuron development, and potential recovery with 7-8 DHF and Selenium.

BKR Gillespie - 2024 - bridges.monash.edu
Infections in pregnancy are a risk factor for the unborn child to develop autism and
schizophrenia later in life. In this thesis, we investigated how infections in pregnancy impact …